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Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation.
Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne TE, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu RT, Downes M, Evans RM, Rydén M, Wabitsch M, Wang Z, Hakozaki H, Schöneberg J, Reilly SM, Huang J, Saltiel AR. Xia W, et al. Among authors: wabitsch m. Nat Metab. 2024 Feb;6(2):273-289. doi: 10.1038/s42255-024-00978-0. Epub 2024 Jan 29. Nat Metab. 2024. PMID: 38286821 Free PMC article.
Obesity-dependent increase in RalA activity disrupts mitochondrial dynamics in white adipocytes.
Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne T, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu R, Downes M, Evans R, Ryden M, Wabitsch M, Reilly S, Huang J, Saltiel A. Xia W, et al. Among authors: wabitsch m. Res Sq [Preprint]. 2023 Jun 2:rs.3.rs-2923510. doi: 10.21203/rs.3.rs-2923510/v1. Res Sq. 2023. Update in: Nat Metab. 2024 Feb;6(2):273-289. doi: 10.1038/s42255-024-00978-0 PMID: 37398165 Free PMC article. Updated. Preprint.
A spatiotemporal proteomic map of human adipogenesis.
Klingelhuber F, Frendo-Cumbo S, Omar-Hmeadi M, Massier L, Kakimoto P, Taylor AJ, Couchet M, Ribicic S, Wabitsch M, Messias AC, Iuso A, Müller TD, Rydén M, Mejhert N, Krahmer N. Klingelhuber F, et al. Among authors: wabitsch m. Nat Metab. 2024 May;6(5):861-879. doi: 10.1038/s42255-024-01025-8. Epub 2024 Apr 2. Nat Metab. 2024. PMID: 38565923 Free PMC article.
Role of CD95-mediated adipocyte loss in autoimmune lipodystrophy.
Fischer-Posovszky P, Hebestreit H, Hofmann AK, Strauss G, Möller P, Debatin KM, Wabitsch M. Fischer-Posovszky P, et al. Among authors: wabitsch m. J Clin Endocrinol Metab. 2006 Mar;91(3):1129-35. doi: 10.1210/jc.2005-0737. Epub 2005 Dec 20. J Clin Endocrinol Metab. 2006. PMID: 16368755
A new missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness.
Fischer-Posovszky P, von Schnurbein J, Moepps B, Lahr G, Strauss G, Barth TF, Kassubek J, Mühleder H, Möller P, Debatin KM, Gierschik P, Wabitsch M. Fischer-Posovszky P, et al. Among authors: wabitsch m. J Clin Endocrinol Metab. 2010 Jun;95(6):2836-40. doi: 10.1210/jc.2009-2466. Epub 2010 Apr 9. J Clin Endocrinol Metab. 2010. PMID: 20382689
Interleukin-1β downregulates RBP4 secretion in human adipocytes.
Kotnik P, Keuper M, Wabitsch M, Fischer-Posovszky P. Kotnik P, et al. Among authors: wabitsch m. PLoS One. 2013;8(2):e57796. doi: 10.1371/journal.pone.0057796. Epub 2013 Feb 27. PLoS One. 2013. PMID: 23460908 Free PMC article.
FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes.
Tews D, Fischer-Posovszky P, Fromme T, Klingenspor M, Fischer J, Rüther U, Marienfeld R, Barth TF, Möller P, Debatin KM, Wabitsch M. Tews D, et al. Among authors: wabitsch m. Endocrinology. 2013 Sep;154(9):3141-51. doi: 10.1210/en.2012-1873. Epub 2013 Jun 10. Endocrinology. 2013. PMID: 23751871
463 results