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Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice.
Dos Santos Alves RP, Timis J, Miller R, Valentine K, Pinto PBA, Gonzalez A, Regla-Nava JA, Maule E, Nguyen MN, Shafee N, Landeras-Bueno S, Olmedillas E, Laffey B, Dobaczewska K, Mikulski Z, McArdle S, Leist SR, Kim K, Baric RS, Ollmann Saphire E, Elong Ngono A, Shresta S. Dos Santos Alves RP, et al. Among authors: timis j. Nat Commun. 2024 Jan 26;15(1):787. doi: 10.1038/s41467-024-45043-2. Nat Commun. 2024. PMID: 38278784 Free PMC article.
SARS-CoV-2 Omicron (B.1.1.529) shows minimal neurotropism in a double-humanized mouse model.
Alves RPDS, Wang YT, Mikulski Z, McArdle S, Shafee N, Valentine KM, Miller R, Verma SK, Batiz FAS, Maule E, Nguyen MN, Timis J, Mann C, Zandonatti M, Alarcon S, Rowe J, Kronenberg M, Weiskopf D, Sette A, Hastie K, Saphire EO, Festin S, Kim K, Shresta S. Alves RPDS, et al. Among authors: timis j. Antiviral Res. 2023 Apr;212:105580. doi: 10.1016/j.antiviral.2023.105580. Epub 2023 Mar 20. Antiviral Res. 2023. PMID: 36940916 Free PMC article.
Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice.
Verma SK, Ana-Sosa-Batiz F, Timis J, Shafee N, Maule E, Pinto PBA, Conner C, Valentine KM, Cowley DO, Miller R, Elong Ngono A, Tran L, Varghese K, Dos Santos Alves RP, Hastie KM, Saphire EO, Webb DR, Jarnagin K, Kim K, Shresta S. Verma SK, et al. Among authors: timis j. EBioMedicine. 2024 Oct;108:105361. doi: 10.1016/j.ebiom.2024.105361. Epub 2024 Sep 30. EBioMedicine. 2024. PMID: 39353281 Free PMC article.