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Scaling behaviours of deep learning and linear algorithms for the prediction of stroke severity.
Bourached A, Bonkhoff AK, Schirmer MD, Regenhardt RW, Bretzner M, Hong S, Dalca AV, Giese AK, Winzeck S, Jern C, Lindgren AG, Maguire J, Wu O, Rhee J, Kimchi EY, Rost NS. Bourached A, et al. Among authors: jern c. Brain Commun. 2024 Jan 10;6(1):fcae007. doi: 10.1093/braincomms/fcae007. eCollection 2024. Brain Commun. 2024. PMID: 38274570 Free PMC article.
Common coding variant in SERPINA1 increases the risk for large artery stroke.
Malik R, Dau T, Gonik M, Sivakumar A, Deredge DJ, Edeleva EV, Götzfried J, van der Laan SW, Pasterkamp G, Beaufort N, Seixas S, Bevan S, Lincz LF, Holliday EG, Burgess AI, Rannikmäe K, Minnerup J, Kriebel J, Waldenberger M, Müller-Nurasyid M, Lichtner P, Saleheen D; International Stroke Genetics Consortium; Rothwell PM, Levi C, Attia J, Sudlow CL, Braun D, Markus HS, Wintrode PL, Berger K, Jenne DE, Dichgans M. Malik R, et al. Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3613-3618. doi: 10.1073/pnas.1616301114. Epub 2017 Mar 6. Proc Natl Acad Sci U S A. 2017. PMID: 28265093 Free PMC article.
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt CO, Sc… See abstract for full author list ➔ Malik R, et al. Among authors: jern c. Nat Genet. 2018 Apr;50(4):524-537. doi: 10.1038/s41588-018-0058-3. Epub 2018 Mar 12. Nat Genet. 2018. PMID: 29531354 Free PMC article.
Prediction of stroke severity: systematic evaluation of lesion representations.
Bonkhoff AK, Cohen AL, Drew W, Ferguson MA, Hussain A, Lin C, Schaper FLWVJ, Bourached A, Giese AK, Oliveira LC, Regenhardt RW, Schirmer MD, Jern C, Lindgren AG, Maguire J, Wu O, Zafar S, Rhee JY, Kimchi EY, Corbetta M, Rost NS, Fox MD; MRI‐GENIE and GISCOME Investigators and the International Stroke Genetics Consortium. Bonkhoff AK, et al. Among authors: jern c. Ann Clin Transl Neurol. 2024 Oct 11. doi: 10.1002/acn3.52215. Online ahead of print. Ann Clin Transl Neurol. 2024. PMID: 39394714 Free article.
Plasma fibrinogen and risk of vascular recurrence after ischaemic stroke: An individual participant and summary-level data meta-analysis of 11 prospective studies.
McCabe JJ, Walsh C, Gorey S, Harris K, Hervella P, Iglesias-Rey R, Jern C, Li L, Miyamoto N, Montaner J, Pedersen A, Purroy F, Rothwell PM, Sudlow C, Ueno Y, Vicente-Pascual M, Whiteley W, Woodward M, Kelly PJ. McCabe JJ, et al. Among authors: jern c. Eur Stroke J. 2024 Sep;9(3):704-713. doi: 10.1177/23969873241246489. Epub 2024 Apr 10. Eur Stroke J. 2024. PMID: 38600679 Free PMC article.
Interleukin-6, C-Reactive Protein, and Recurrence After Stroke: A Time-Course Analysis of Individual-Participant Data.
McCabe JJ, Walsh C, Gorey S, Arnold M, DeMarchis GM, Harris K, Hervella P, Iglesias-Rey R, Jern C, Katan M, Li L, Miyamoto N, Montaner J, Purroy F, Rothwell PM, Stanne TM, Sudlow C, Ueno Y, Vicente-Pascual M, Whiteley W, Woodward M, Kelly PJ. McCabe JJ, et al. Among authors: jern c. Stroke. 2024 Oct 31. doi: 10.1161/STROKEAHA.124.047820. Online ahead of print. Stroke. 2024. PMID: 39479747
The genetic landscape of neuro-related proteins in human plasma.
Repetto L, Chen J, Yang Z, Zhai R, Timmers PRHJ, Feng X, Li T, Yao Y, Maslov D, Timoshchuk A, Tu F, Twait EL, May-Wilson S, Muckian MD, Prins BP, Png G, Kooperberg C, Johansson Å, Hillary RF, Wheeler E, Pan L, He Y, Klasson S, Ahmad S, Peters JE, Gilly A, Karaleftheri M, Tsafantakis E, Haessler J, Gyllensten U, Harris SE, Wareham NJ, Göteson A, Lagging C, Ikram MA, van Duijn CM, Jern C, Landén M, Langenberg C, Deary IJ, Marioni RE, Enroth S, Reiner AP, Dedoussis G, Zeggini E, Sharapov S, Aulchenko YS, Butterworth AS, Mälarstig A, Wilson JF, Navarro P, Shen X. Repetto L, et al. Among authors: jern c. Nat Hum Behav. 2024 Aug 29. doi: 10.1038/s41562-024-01963-z. Online ahead of print. Nat Hum Behav. 2024. PMID: 39210026
210 results