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Page 1
Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Rajendiran V, Devaraju N, Haddad M, Ravi NS, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AA, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S, Velayudhan SR, Corn JE, Mackay JP, Marepally S, Srivastava A, Crossley M, Mohankumar KM. Rajendiran V, et al. Among authors: pai aa. Mol Ther. 2024 Mar 6;32(3):663-677. doi: 10.1016/j.ymthe.2024.01.023. Epub 2024 Jan 24. Mol Ther. 2024. PMID: 38273654 Free article.
Pharmacokinetics and Efficacy of Generic Melphalan Is Comparable to Innovator Formulation in Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplantation.
Pai AA, Devasia AJ, Panetta JC, Mani S, Stallon Illangeswaran RS, Mohanan E, Balakrishnan B, Lakshmi KM, Kulkarni U, Aboobacker FN, Korula A, Abraham A, Srivastava A, Mathews V, George B, Balasubramanian P. Pai AA, et al. Clin Lymphoma Myeloma Leuk. 2020 Feb;20(2):130-135.e1. doi: 10.1016/j.clml.2019.08.013. Epub 2019 Oct 4. Clin Lymphoma Myeloma Leuk. 2020. PMID: 31791694 Free PMC article.
Prognostic plasma biomarkers of early complications and graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantation.
Balakrishnan B, Illangeswaran RSS, Rajamani BM, Pai AA, Raj IX, Paul DZ, Lakshmi K, Mani T, Mohanan E, Kulkarni U, Devasia AJ, Fouzia NA, Korula A, Abraham A, Srivastava A, Mathews V, Paczesny S, George B, Balasubramanian P. Balakrishnan B, et al. Among authors: pai aa. EJHaem. 2020 Jul;1(1):219-229. doi: 10.1002/jha2.26. Epub 2020 Jun 17. EJHaem. 2020. PMID: 32885223 Free PMC article.
NUDT15 c.415C>T Polymorphism Predicts 6-MP Induced Early Myelotoxicity in Patients with Acute Lymphoblastic Leukemia Undergoing Maintenance Therapy.
Pai AA, Mohan A, Benjamin ESB, Illangeswaran RSS, Xavier Raj I, Janet NB, Arunachalam AK, Kavitha ML, Kulkarni U, Devasia AJ, Fouzia NA, Abraham A, Srivastava A, George B, Mathews V, Korula A, Balasubramanian P. Pai AA, et al. Pharmgenomics Pers Med. 2021 Oct 2;14:1303-1313. doi: 10.2147/PGPM.S325813. eCollection 2021. Pharmgenomics Pers Med. 2021. PMID: 34629890 Free PMC article.
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Ravi NS, Wienert B, Wyman SK, Bell HW, George A, Mahalingam G, Vu JT, Prasad K, Bandlamudi BP, Devaraju N, Rajendiran V, Syedbasha N, Pai AA, Nakamura Y, Kurita R, Narayanasamy M, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, DeWitt MA, Crossley M, Corn JE, Mohankumar KM. Ravi NS, et al. Among authors: pai aa. Elife. 2022 Feb 11;11:e65421. doi: 10.7554/eLife.65421. Elife. 2022. PMID: 35147495 Free PMC article.
Endothelial Activation and Stress Index-Measured Pretransplantation Predicts Transplantation-Related Mortality in Patients with Thalassemia Major Undergoing Transplantation with Thiotepa, Treosulfan, and Fludarabine Conditioning.
Kulkarni UP, Pai AA, Kavitha ML, Selvarajan S, Lionel S, Devasia AJ, Korula A, Fouzia NA, Sindhuvi E, Abraham A, Srivastava A, Mathews V, George B, Balasubramanian P. Kulkarni UP, et al. Among authors: pai aa. Transplant Cell Ther. 2022 Jul;28(7):356.e1-356.e6. doi: 10.1016/j.jtct.2022.05.001. Epub 2022 May 9. Transplant Cell Ther. 2022. PMID: 35550442 Free article.
Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.
Bagchi A, Devaraju N, Chambayil K, Rajendiran V, Venkatesan V, Sayed N, Pai AA, Nath A, David E, Nakamura Y, Balasubramanian P, Srivastava A, Thangavel S, Mohankumar KM, Velayudhan SR. Bagchi A, et al. Among authors: pai aa. Sci Rep. 2022 Aug 18;12(1):14033. doi: 10.1038/s41598-022-13783-0. Sci Rep. 2022. PMID: 35982069 Free PMC article.
Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.
George A, Ravi NS, Prasad K, Panigrahi L, Koikkara S, Rajendiran V, Devaraju N, Paul J, Pai AA, Nakamura Y, Kurita R, Balasubramanian P, Thangavel S, Marepally S, Velayudhan SR, Srivastava A, Mohankumar KM. George A, et al. Among authors: pai aa. Front Genome Ed. 2022 Dec 20;4:1085111. doi: 10.3389/fgeed.2022.1085111. eCollection 2022. Front Genome Ed. 2022. PMID: 36605051 Free PMC article.
65 results