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SARS-CoV-2 infection causes dopaminergic neuron senescence.
Yang L, Kim TW, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SY, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Pan C, Wu J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler O'Brien RL, Bugiani M, D J Van de Berg W, Schwartz RE, Ho DD, Studer L, Chen S. Yang L, et al. Among authors: ho dd. Cell Stem Cell. 2024 Feb 1;31(2):196-211.e6. doi: 10.1016/j.stem.2023.12.012. Epub 2024 Jan 17. Cell Stem Cell. 2024. PMID: 38237586 Free PMC article.
Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain.
Cerutti G, Guo Y, Wang P, Nair MS, Huang Y, Yu J, Liu L, Katsamba PS, Bahna F, Reddem ER, Kwong PD, Ho DD, Sheng Z, Shapiro L. Cerutti G, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Jun 29:2021.06.29.450397. doi: 10.1101/2021.06.29.450397. bioRxiv. 2021. Update in: Cell Rep. 2021 Nov 2;37(5):109928. doi: 10.1016/j.celrep.2021.109928. PMID: 34230927 Free PMC article. Updated. Preprint.
A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses.
Wang P, Casner RG, Nair MS, Yu J, Guo Y, Wang M, Chan JF, Cerutti G, Iketani S, Liu L, Sheng Z, Chen Z, Yuen KY, Kwong PD, Huang Y, Shapiro L, Ho DD. Wang P, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Oct 14:2021.10.13.464307. doi: 10.1101/2021.10.13.464307. bioRxiv. 2021. Update in: Emerg Microbes Infect. 2022 Dec;11(1):147-157. doi: 10.1080/22221751.2021.2011623. PMID: 34671769 Free PMC article. Updated. Preprint.
Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study.
Hay JA, Kissler SM, Fauver JR, Mack C, Tai CG, Samant RM, Connolly S, Anderson DJ, Khullar G, MacKay M, Patel M, Kelly S, Manhertz A, Eiter I, Salgado D, Baker T, Howard B, Dudley JT, Mason CE, Nair M, Huang Y, DiFiori J, Ho DD, Grubaugh ND, Grad YH. Hay JA, et al. Among authors: ho dd. Elife. 2022 Nov 16;11:e81849. doi: 10.7554/eLife.81849. Elife. 2022. PMID: 36383192 Free PMC article.
Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking.
Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Liu L, et al. Among authors: ho dd. Immunity. 2023 Oct 10;56(10):2442-2455.e8. doi: 10.1016/j.immuni.2023.09.003. Epub 2023 Sep 29. Immunity. 2023. PMID: 37776849 Free PMC article.
Developing inhibitory peptides against SARS-CoV-2 envelope protein.
Bekdash R, Yoshida K, Nair MS, Qiu L, Ahdout J, Tsai HY, Uryu K, Soni RK, Huang Y, Ho DD, Yazawa M. Bekdash R, et al. Among authors: ho dd. PLoS Biol. 2024 Mar 14;22(3):e3002522. doi: 10.1371/journal.pbio.3002522. eCollection 2024 Mar. PLoS Biol. 2024. PMID: 38483887 Free PMC article.
Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants.
Wang Q, Iketani S, Li Z, Liu L, Guo Y, Huang Y, Bowen AD, Liu M, Wang M, Yu J, Valdez R, Lauring AS, Sheng Z, Wang HH, Gordon A, Liu L, Ho DD. Wang Q, et al. Among authors: ho dd. Cell. 2023 Jan 19;186(2):279-286.e8. doi: 10.1016/j.cell.2022.12.018. Epub 2022 Dec 14. Cell. 2023. PMID: 36580913 Free PMC article.
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Chu HY, Neher RA, Bloom JD. Dadonaite B, et al. Among authors: ho dd. Cell. 2023 Mar 16;186(6):1263-1278.e20. doi: 10.1016/j.cell.2023.02.001. Epub 2023 Feb 13. Cell. 2023. PMID: 36868218 Free PMC article.
461 results