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Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity.
Benede N, Tincho MB, Walters A, Subbiah V, Ngomti A, Baguma R, Butters C, Hahnle L, Mennen M, Skelem S, Adriaanse M, Facey-Thomas H, Scott C, Day J, Spracklen TF, van Graan S, Balla SR, Moyo-Gwete T, Moore PL, MacGinty R, Botha M, Workman L, Johnson M, Goldblatt D, Zar HJ, Ntusi NAB, Zühlke L, Webb K, Riou C, Burgers WA, Keeton RS. Benede N, et al. Among authors: spracklen tf. iScience. 2023 Dec 14;27(1):108728. doi: 10.1016/j.isci.2023.108728. eCollection 2024 Jan 19. iScience. 2023. PMID: 38235336 Free PMC article.
Comparing the immune abnormalities in MIS-C to healthy children and those with inflammatory disease reveals distinct inflammatory cytokine production and a monofunctional T cell response.
Butters C, Benede N, Moyo-Gwete T, Richardson SI, Rohlwink U, Shey M, Ayres F, Manamela NP, Makhado Z, Balla SR, Madzivhandila M, Ngomti A, Baguma R, Facey-Thomas H, Spracklen TF, Day J, van der Ross H, Riou C, Burgers WA, Scott C, Zühlke L, Moore PL, Keeton RS, Webb K. Butters C, et al. Among authors: spracklen tf. Clin Immunol. 2024 Feb;259:109877. doi: 10.1016/j.clim.2023.109877. Epub 2023 Dec 22. Clin Immunol. 2024. PMID: 38141746 Free article.
Investigation of Copy Number Variation in South African Patients With Congenital Heart Defects.
Saacks NA, Eales J, Spracklen TF, Aldersley T, Human P, Verryn M, Lawrenson J, Cupido B, Comitis G, De Decker R, Fourie B, Swanson L, Joachim A, Brooks A, Ramesar R, Shaboodien G, Keavney BD, Zühlke LJ. Saacks NA, et al. Among authors: spracklen tf. Circ Genom Precis Med. 2022 Dec;15(6):e003510. doi: 10.1161/CIRCGEN.121.003510. Epub 2022 Oct 7. Circ Genom Precis Med. 2022. PMID: 36205932 Free PMC article.
Peripartum cardiomyopathy: from genetics to management.
Sliwa K, Bauersachs J, Arany Z, Spracklen TF, Hilfiker-Kleiner D. Sliwa K, et al. Among authors: spracklen tf. Eur Heart J. 2021 Aug 21;42(32):3094-3102. doi: 10.1093/eurheartj/ehab458. Eur Heart J. 2021. PMID: 34322694 Review.
Genetics of inherited cardiomyopathies in Africa.
Shaboodien G, Spracklen TF, Kamuli S, Ndibangwi P, Van Niekerk C, Ntusi NAB. Shaboodien G, et al. Among authors: spracklen tf. Cardiovasc Diagn Ther. 2020 Apr;10(2):262-278. doi: 10.21037/cdt.2019.10.03. Cardiovasc Diagn Ther. 2020. PMID: 32420109 Free PMC article. Review.
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