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TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2.
Yang CB, Liu J, Tong BC, Wang ZY, Zhu Z, Su CF, Sreenivasmurthy SG, Wu JX, Iyaswamy A, Krishnamoorthi S, Huang SY, Cheung KH, Song JX, Tan JQ, Lu JH, Li M. Yang CB, et al. Among authors: tong bc. Acta Pharmacol Sin. 2022 May;43(5):1251-1263. doi: 10.1038/s41401-021-00711-7. Epub 2021 Aug 20. Acta Pharmacol Sin. 2022. PMID: 34417577 Free PMC article.
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.
Zhu Z, Liu LF, Su CF, Liu J, Tong BC, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Guan XJ, Kan YX, Xie WJ, Zhao CL, Cheung KH, Lu JH, Tan JQ, Zhang HJ, Song JX, Li M. Zhu Z, et al. Among authors: tong bc. Acta Pharmacol Sin. 2022 Oct;43(10):2511-2526. doi: 10.1038/s41401-022-00871-0. Epub 2022 Feb 25. Acta Pharmacol Sin. 2022. PMID: 35217810 Free PMC article.
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models.
Iyaswamy A, Wang X, Krishnamoorthi S, Kaliamoorthy V, Sreenivasmurthy SG, Kumar Durairajan SS, Song JX, Tong BC, Zhu Z, Su CF, Liu J, Cheung KH, Lu JH, Tan JQ, Li HW, Wong MS, Li M. Iyaswamy A, et al. Among authors: tong bc. Redox Biol. 2022 May;51:102280. doi: 10.1016/j.redox.2022.102280. Epub 2022 Mar 8. Redox Biol. 2022. PMID: 35286997 Free PMC article.
Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy.
Yang C, Su C, Iyaswamy A, Krishnamoorthi SK, Zhu Z, Yang S, Tong BC, Liu J, Sreenivasmurthy SG, Guan X, Kan Y, Wu AJ, Huang AS, Tan J, Cheung K, Song J, Li M. Yang C, et al. Among authors: tong bc. Acta Pharm Sin B. 2022 Apr;12(4):1707-1722. doi: 10.1016/j.apsb.2022.01.017. Epub 2022 Feb 3. Acta Pharm Sin B. 2022. PMID: 35847498 Free PMC article.
Calcium signaling in Alzheimer's disease & therapies.
Tong BC, Wu AJ, Li M, Cheung KH. Tong BC, et al. Biochim Biophys Acta Mol Cell Res. 2018 Nov;1865(11 Pt B):1745-1760. doi: 10.1016/j.bbamcr.2018.07.018. Epub 2018 Jul 29. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 30059692 Free article. Review.
Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson's Disease.
Zhu Z, Yang C, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Liu J, Wang Z, Tong BC, Song J, Lu J, Cheung KH, Li M. Zhu Z, et al. Among authors: tong bc. Int J Mol Sci. 2019 Feb 8;20(3):728. doi: 10.3390/ijms20030728. Int J Mol Sci. 2019. PMID: 30744070 Free PMC article. Review.
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.
Song JX, Malampati S, Zeng Y, Durairajan SSK, Yang CB, Tong BC, Iyaswamy A, Shang WB, Sreenivasmurthy SG, Zhu Z, Cheung KH, Lu JH, Tang C, Xu N, Li M. Song JX, et al. Among authors: tong bc. Aging Cell. 2020 Feb;19(2):e13069. doi: 10.1111/acel.13069. Epub 2019 Dec 19. Aging Cell. 2020. PMID: 31858697 Free PMC article.
NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models.
Iyaswamy A, Krishnamoorthi SK, Song JX, Yang CB, Kaliyamoorthy V, Zhang H, Sreenivasmurthy SG, Malampati S, Wang ZY, Zhu Z, Tong BC, Cheung KH, Lu JH, Durairajan SSK, Li M. Iyaswamy A, et al. Among authors: tong bc. J Food Drug Anal. 2020 Jan;28(1):132-146. doi: 10.1016/j.jfda.2019.09.004. Epub 2019 Oct 8. J Food Drug Anal. 2020. PMID: 31883601 Free article.
177 results