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Page 1
PPARɑ Ligand Caudatin Improves Cognitive Functions and Mitigates Alzheimer's Disease Defects By Inducing Autophagy in Mice Models.
Krishnamoorthi S, Iyaswamy A, Sreenivasmurthy SG, Thakur A, Vasudevan K, Kumar G, Guan XJ, Lu K, Gaurav I, Su CF, Zhu Z, Liu J, Kan Y, Jayaraman S, Deng Z, Chua KK, Cheung KH, Yang Z, Song JX, Li M. Krishnamoorthi S, et al. J Neuroimmune Pharmacol. 2023 Sep;18(3):509-528. doi: 10.1007/s11481-023-10083-w. Epub 2023 Sep 8. J Neuroimmune Pharmacol. 2023. PMID: 37682502
Molecular engineering of a theranostic molecule that detects Aβ plaques, inhibits Iowa and Dutch mutation Aβ self-aggregation and promotes lysosomal biogenesis for Alzheimer's disease.
Iyaswamy A, Wang X, Zhang H, Vasudevan K, Wankhar D, Lu K, Krishnamoorthi S, Guan XJ, Su CF, Liu J, Kan Y, Jaganathan R, Deng Z, Li HW, Wong MS, Li M. Iyaswamy A, et al. J Mater Chem B. 2024 Aug 7;12(31):7543-7556. doi: 10.1039/d4tb00479e. J Mater Chem B. 2024. PMID: 38978513
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.
Zhu Z, Liu LF, Su CF, Liu J, Tong BC, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Guan XJ, Kan YX, Xie WJ, Zhao CL, Cheung KH, Lu JH, Tan JQ, Zhang HJ, Song JX, Li M. Zhu Z, et al. Among authors: kan yx. Acta Pharmacol Sin. 2022 Oct;43(10):2511-2526. doi: 10.1038/s41401-022-00871-0. Epub 2022 Feb 25. Acta Pharmacol Sin. 2022. PMID: 35217810 Free PMC article.