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Page 1
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes.
Johnson BB, Cosson MV, Tsansizi LI, Holmes TL, Gilmore T, Hampton K, Song OR, Vo NTN, Nasir A, Chabronova A, Denning C, Peffers MJ, Merry CLR, Whitelock J, Troeberg L, Rushworth SA, Bernardo AS, Smith JGW. Johnson BB, et al. Among authors: smith jgw. Cell Rep. 2024 Jan 23;43(1):113668. doi: 10.1016/j.celrep.2023.113668. Epub 2024 Jan 9. Cell Rep. 2024. PMID: 38198277 Free article.
Chemically diverse polymer microarrays and high throughput surface characterisation: a method for discovery of materials for stem cell culture†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4bm00054dClick here for additional data file.
Celiz AD, Smith JG, Patel AK, Langer R, Anderson DG, Barrett DA, Young LE, Davies MC, Denning C, Alexander MR. Celiz AD, et al. Biomater Sci. 2014 Nov 30;2(11):1604-1611. doi: 10.1039/c4bm00054d. Epub 2014 May 12. Biomater Sci. 2014. PMID: 25328672 Free PMC article.
Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.
Denning C, Borgdorff V, Crutchley J, Firth KS, George V, Kalra S, Kondrashov A, Hoang MD, Mosqueira D, Patel A, Prodanov L, Rajamohan D, Skarnes WC, Smith JG, Young LE. Denning C, et al. Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1728-48. doi: 10.1016/j.bbamcr.2015.10.014. Epub 2015 Oct 31. Biochim Biophys Acta. 2016. PMID: 26524115 Free PMC article.
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy.
Mosqueira D, Mannhardt I, Bhagwan JR, Lis-Slimak K, Katili P, Scott E, Hassan M, Prondzynski M, Harmer SC, Tinker A, Smith JGW, Carrier L, Williams PM, Gaffney D, Eschenhagen T, Hansen A, Denning C. Mosqueira D, et al. Among authors: smith jgw. Eur Heart J. 2018 Nov 14;39(43):3879-3892. doi: 10.1093/eurheartj/ehy249. Eur Heart J. 2018. PMID: 29741611 Free PMC article.
Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits.
Smith JGW, Owen T, Bhagwan JR, Mosqueira D, Scott E, Mannhardt I, Patel A, Barriales-Villa R, Monserrat L, Hansen A, Eschenhagen T, Harding SE, Marston S, Denning C. Smith JGW, et al. Stem Cell Reports. 2018 Nov 13;11(5):1226-1243. doi: 10.1016/j.stemcr.2018.10.006. Epub 2018 Nov 1. Stem Cell Reports. 2018. PMID: 30392975 Free PMC article.
ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection.
Mistry JJ, Marlein CR, Moore JA, Hellmich C, Wojtowicz EE, Smith JGW, Macaulay I, Sun Y, Morfakis A, Patterson A, Horton RH, Divekar D, Morris CJ, Haestier A, Di Palma F, Beraza N, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: smith jgw. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24610-24619. doi: 10.1073/pnas.1913278116. Epub 2019 Nov 14. Proc Natl Acad Sci U S A. 2019. PMID: 31727843 Free PMC article.
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