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Within-subject changes in methylome profile identify individual signatures of early-life adversity, with a potential to predict neuropsychiatric outcome.
Short AK, Weber R, Kamei N, Thai CW, Arora H, Mortazavi A, Stern HS, Glynn L, Baram TZ. Short AK, et al. bioRxiv [Preprint]. 2023 Dec 19:2023.12.16.571594. doi: 10.1101/2023.12.16.571594. bioRxiv. 2023. Update in: Neurobiol Stress. 2024 May 31;31:100652. doi: 10.1016/j.ynstr.2024.100652. PMID: 38187766 Free PMC article. Updated. Preprint.
Early life adversity in male mice sculpts reward circuits.
Wendel KM, Short AK, Noarbe BP, Haddad E, Palma AM, Yassa MA, Baram TZ, Obenaus A. Wendel KM, et al. Among authors: short ak. Neurobiol Stress. 2021 Oct 16;15:100409. doi: 10.1016/j.ynstr.2021.100409. eCollection 2021 Nov. Neurobiol Stress. 2021. PMID: 34746338 Free PMC article.
Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses.
Bolton JL, Short AK, Othy S, Kooiker CL, Shao M, Gunn BG, Beck J, Bai X, Law SM, Savage JC, Lambert JJ, Belelli D, Tremblay MÈ, Cahalan MD, Baram TZ. Bolton JL, et al. Among authors: short ak. Cell Rep. 2022 Mar 29;38(13):110600. doi: 10.1016/j.celrep.2022.110600. Cell Rep. 2022. PMID: 35354026 Free PMC article.
42 results