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Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Deen AJ, Adinolfi S, Härkönen J, Patinen T, Liu X, Laitinen T, Takabe P, Kainulainen K, Pasonen-Seppänen S, Gawriyski LM, Arasu UT, Selvarajan I, Mäkinen P, Laitinen H, Kansanen E, Kaikkonen MU, Poso A, Varjosalo M, Levonen AL. Deen AJ, et al. Among authors: patinen t. Redox Biol. 2024 Feb;69:103031. doi: 10.1016/j.redox.2024.103031. Epub 2024 Jan 4. Redox Biol. 2024. PMID: 38184997 Free PMC article.
The KEAP1-NRF2 pathway: Targets for therapy and role in cancer.
Adinolfi S, Patinen T, Jawahar Deen A, Pitkänen S, Härkönen J, Kansanen E, Küblbeck J, Levonen AL. Adinolfi S, et al. Among authors: patinen t. Redox Biol. 2023 Jul;63:102726. doi: 10.1016/j.redox.2023.102726. Epub 2023 Apr 29. Redox Biol. 2023. PMID: 37146513 Free PMC article. Review.
Regulation of stress signaling pathways by protein lipoxidation.
Patinen T, Adinolfi S, Cortés CC, Härkönen J, Jawahar Deen A, Levonen AL. Patinen T, et al. Redox Biol. 2019 May;23:101114. doi: 10.1016/j.redox.2019.101114. Epub 2019 Jan 16. Redox Biol. 2019. PMID: 30709792 Free PMC article. Review.
Regulation of stress signaling pathways by nitro-fatty acids.
Deen AJ, Sihvola V, Härkönen J, Patinen T, Adinolfi S, Levonen AL. Deen AJ, et al. Among authors: patinen t. Nitric Oxide. 2018 Mar 19:S1089-8603(17)30323-3. doi: 10.1016/j.niox.2018.03.012. Online ahead of print. Nitric Oxide. 2018. PMID: 29567143 Review.