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Page 1
DnaB and DciA: Mechanisms of Helicase Loading and Translocation on ssDNA.
Gao N, Mazzoletti D, Peng A, Olinares PDB, Morrone C, Garavaglia A, Gouda N, Tsoy S, Mendoza A, Chowdhury A, Cerullo A, Bhavsar H, Rossi F, Rizzi M, Chait BT, Miggiano R, Jeruzalmi D. Gao N, et al. Among authors: chait bt. bioRxiv [Preprint]. 2024 Nov 9:2024.11.09.622779. doi: 10.1101/2024.11.09.622779. bioRxiv. 2024. PMID: 39574654 Free PMC article. Preprint.
Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA.
Chua GNL, Watters JW, Olinares PDB, Begum M, Vostal LE, Luo JA, Chait BT, Liu S. Chua GNL, et al. Among authors: chait bt. Nat Struct Mol Biol. 2024 Nov;31(11):1789-1797. doi: 10.1038/s41594-024-01373-9. Epub 2024 Aug 20. Nat Struct Mol Biol. 2024. PMID: 39164525 Free PMC article.
The molecular architecture of the nuclear basket.
Singh D, Soni N, Hutchings J, Echeverria I, Shaikh F, Duquette M, Suslov S, Li Z, van Eeuwen T, Molloy K, Shi Y, Wang J, Guo Q, Chait BT, Fernandez-Martinez J, Rout MP, Sali A, Villa E. Singh D, et al. Among authors: chait bt. Cell. 2024 Sep 19;187(19):5267-5281.e13. doi: 10.1016/j.cell.2024.07.020. Epub 2024 Aug 9. Cell. 2024. PMID: 39127037 Free PMC article.
A lineage-specific protein network at the trypanosome nuclear envelope.
Butterfield ER, Obado SO, Scutts SR, Zhang W, Chait BT, Rout MP, Field MC. Butterfield ER, et al. Among authors: chait bt. Nucleus. 2024 Dec;15(1):2310452. doi: 10.1080/19491034.2024.2310452. Epub 2024 Apr 11. Nucleus. 2024. PMID: 38605598 Free PMC article.
The Molecular Architecture of the Nuclear Basket.
Singh D, Soni N, Hutchings J, Echeverria I, Shaikh F, Duquette M, Suslov S, Li Z, van Eeuwen T, Molloy K, Shi Y, Wang J, Guo Q, Chait BT, Fernandez-Martinez J, Rout MP, Sali A, Villa E. Singh D, et al. Among authors: chait bt. bioRxiv [Preprint]. 2024 Mar 28:2024.03.27.587068. doi: 10.1101/2024.03.27.587068. bioRxiv. 2024. Update in: Cell. 2024 Sep 19;187(19):5267-5281.e13. doi: 10.1016/j.cell.2024.07.020. PMID: 38586009 Free PMC article. Updated. Preprint.
Using a Function-First "Scout Fragment"-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes.
Ramsey JR, Shelton PMM, Heiss TK, Olinares PDB, Vostal LE, Soileau H, Grasso M, Casebeer SW, Adaniya S, Miller M, Sun S, Huggins DJ, Myers RW, Chait BT, Vinogradova EV, Kapoor TM. Ramsey JR, et al. Among authors: chait bt. J Am Chem Soc. 2024 Jan 10;146(1):62-67. doi: 10.1021/jacs.3c10581. Epub 2023 Dec 22. J Am Chem Soc. 2024. PMID: 38134034
390 results