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Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
Ben-Ami R, Wang QL, Zhang J, Supplee JG, Fahrmann JF, Lehmann-Werman R, Brais LK, Nowak J, Yuan C, Loftus M, Babic A, Irajizad E, Davidi T, Zick A, Hubert A, Neiman D, Piyanzin S, Gal-Rosenberg O, Horn A, Shemer R, Glaser B, Boos N, Jajoo K, Lee L, Clancy TE, Rubinson DA, Ng K, Chabot JA, Kastrinos F, Kluger M, Aguirre AJ, Jänne PA, Bardeesy N, Stanger B, O'Hara MH, Till J, Maitra A, Carpenter EL, Bullock AJ, Genkinger J, Hanash SM, Paweletz CP, Dor Y, Wolpin BM. Ben-Ami R, et al. Among authors: fahrmann jf. Gut. 2024 Mar 7;73(4):639-648. doi: 10.1136/gutjnl-2023-331074. Gut. 2024. PMID: 38123998 Free PMC article.
Integrated spatial transcriptomics and lipidomics of precursor lesions of pancreatic cancer identifies enrichment of long chain sulfatide biosynthesis as an early metabolic alteration.
Sans M, Chen Y, Thege FI, Dou R, Min J, Yip-Schneider M, Zhang J, Wu R, Irajizad E, Makino Y, Rajapakshe KI, Hurd MW, León-Letelier RA, Vykoukal J, Dennison JB, Do KA, Wolff RA, Guerrero PA, Kim MP, Schmidt CM, Maitra A, Hanash S, Fahrmann JF. Sans M, et al. Among authors: fahrmann jf. bioRxiv [Preprint]. 2023 Aug 15:2023.08.14.553002. doi: 10.1101/2023.08.14.553002. bioRxiv. 2023. PMID: 37645752 Free PMC article. Preprint.
A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone.
Haab B, Qian L, Staal B, Jain M, Fahrmann J, Worthington C, Prosser D, Velokokhatnaya L, Lopez C, Tang R, Hurd MW, Natarajan G, Kumar S, Smith L, Hanash S, Batra SK, Maitra A, Lokshin A, Huang Y, Brand RE. Haab B, et al. Cancer Lett. 2024 Nov 1;604:217245. doi: 10.1016/j.canlet.2024.217245. Epub 2024 Sep 12. Cancer Lett. 2024. PMID: 39276915 Free article.
A Rigorous Multi-Laboratory Study of Known PDAC Biomarkers Identifies Increased Sensitivity and Specificity Over CA19-9 Alone.
Haab B, Qian L, Staal B, Jain M, Fahrmann J, Worthington C, Prosser D, Velokokhatnaya L, Lopez C, Tang R, Hurd MW, Natarajan G, Kumar S, Smith L, Hanash S, Batra SK, Maitra A, Lokshin A, Huang Y, Brand RE. Haab B, et al. bioRxiv [Preprint]. 2024 May 26:2024.05.22.595399. doi: 10.1101/2024.05.22.595399. bioRxiv. 2024. Update in: Cancer Lett. 2024 Nov 1;604:217245. doi: 10.1016/j.canlet.2024.217245. PMID: 38826212 Free PMC article. Updated. Preprint.
Low-density lipoprotein electronegativity and risk of death after acute coronary syndromes: A case-cohort analysis.
Kraler S, Wenzl FA, Vykoukal J, Fahrmann JF, Shen MY, Chen DY, Chang KC, Chang CK, von Eckardstein A, Räber L, Mach F, Nanchen D, Matter CM, Liberale L, Camici GG, Akhmedov A, Chen CH, Lüscher TF; SPUM-ACS investigators. Kraler S, et al. Among authors: fahrmann jf. Atherosclerosis. 2023 Jul;376:43-52. doi: 10.1016/j.atherosclerosis.2023.05.014. Epub 2023 May 24. Atherosclerosis. 2023. PMID: 37285778 Free article.
Glycosylation in cancer as a source of biomarkers.
Khorami-Sarvestani S, Hanash SM, Fahrmann JF, León-Letelier RA, Katayama H. Khorami-Sarvestani S, et al. Among authors: fahrmann jf. Expert Rev Proteomics. 2024 Oct 24:1-21. doi: 10.1080/14789450.2024.2409224. Online ahead of print. Expert Rev Proteomics. 2024. PMID: 39376081 Review.
Biomarker trajectory for earlier detection of lung cancer.
Irajizad E, Fahrmann JF, Toumazis I, Vykoukal J, Dennison JB, Shen Y, Do KA, Ostrin EJ, Feng Z, Hanash S. Irajizad E, et al. Among authors: fahrmann jf. EBioMedicine. 2024 Oct;108:105377. doi: 10.1016/j.ebiom.2024.105377. Epub 2024 Sep 30. EBioMedicine. 2024. PMID: 39353277 Free PMC article.
A metabolite-based liquid biopsy for detection of ovarian cancer.
Fahrmann JF, Ghasemi SM, Han CY, Wu R, Dennison JB, Vykoukal J, Celestino J, Lu K, Lu Z, Drescher C, Do KA, Hanash S, Bast RC, Irajizad E. Fahrmann JF, et al. Biomark Res. 2024 Aug 28;12(1):91. doi: 10.1186/s40364-024-00629-2. Biomark Res. 2024. PMID: 39192316 Free PMC article.
76 results