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Page 1
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors.
Donati G, Viviano M, D'Amore VM, Cipriano A, Diakogiannaki I, Amato J, Tomassi S, Brancaccio D, Russomanno P, Di Leva FS, Arosio D, Seneci P, Taliani S, Magiera-Mularz K, Musielak B, Skalniak L, Holak TA, Castellano S, La Pietra V, Marinelli L. Donati G, et al. Among authors: russomanno p. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300583. doi: 10.1002/ardp.202300583. Epub 2023 Dec 18. Arch Pharm (Weinheim). 2024. PMID: 38110703 Free article.
Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders.
D'Aria F, D'Amore VM, Di Leva FS, Amato J, Caterino M, Russomanno P, Salerno S, Barresi E, De Leo M, Marini AM, Taliani S, Da Settimo F, Salgado GF, Pompili L, Zizza P, Shirasawa S, Novellino E, Biroccio A, Marinelli L, Giancola C. D'Aria F, et al. Among authors: russomanno p. Eur J Pharm Sci. 2020 Apr 18;149:105337. doi: 10.1016/j.ejps.2020.105337. Online ahead of print. Eur J Pharm Sci. 2020. PMID: 32311457
HOPPI-NMR: Hot-Peptide-Based Screening Assay for Inhibitors of Protein-Protein Interactions by NMR.
Brancaccio D, Di Maro S, Cerofolini L, Giuntini S, Fragai M, Luchinat C, Tomassi S, Limatola A, Russomanno P, Merlino F, Novellino E, Carotenuto A. Brancaccio D, et al. Among authors: russomanno p. ACS Med Chem Lett. 2020 Feb 20;11(5):1047-1053. doi: 10.1021/acsmedchemlett.9b00620. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435424 Free PMC article.
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme.
Daniele S, La Pietra V, Piccarducci R, Pietrobono D, Cavallini C, D'Amore VM, Cerofolini L, Giuntini S, Russomanno P, Puxeddu M, Nalli M, Pedrini M, Fragai M, Luchinat C, Novellino E, Taliani S, La Regina G, Silvestri R, Martini C, Marinelli L. Daniele S, et al. Among authors: russomanno p. Eur J Pharmacol. 2021 Apr 15;897:173936. doi: 10.1016/j.ejphar.2021.173936. Epub 2021 Feb 10. Eur J Pharmacol. 2021. PMID: 33581134
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors.
Russomanno P, Assoni G, Amato J, D'Amore VM, Scaglia R, Brancaccio D, Pedrini M, Polcaro G, La Pietra V, Orlando P, Falzoni M, Cerofolini L, Giuntini S, Fragai M, Pagano B, Donati G, Novellino E, Quintavalle C, Condorelli G, Sabbatino F, Seneci P, Arosio D, Pepe S, Marinelli L. Russomanno P, et al. J Med Chem. 2021 Nov 11;64(21):16020-16045. doi: 10.1021/acs.jmedchem.1c01409. Epub 2021 Oct 20. J Med Chem. 2021. PMID: 34670084
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design.
Donati G, D'Amore VM, Russomanno P, Cerofolini L, Amato J, Marzano S, Salobehaj M, Rizzo D, Assoni G, Carotenuto A, La Pietra V, Arosio D, Seneci P, Fragai M, Brancaccio D, Di Leva FS, Marinelli L. Donati G, et al. Among authors: russomanno p. Comput Struct Biotechnol J. 2023 Jun 8;21:3355-3368. doi: 10.1016/j.csbj.2023.06.006. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37384351 Free PMC article.
Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists.
Russo C, Russomanno P, D'Amore VM, Alfano AI, Santoro F, Guzelj S, Gobec M, Amato J, Pagano B, Marinelli L, Carotenuto A, Tron GC, Di Leva FS, Jakopin Ž, Brancaccio D, Giustiniano M. Russo C, et al. Among authors: russomanno p. J Med Chem. 2024 Feb 22;67(4):3004-3017. doi: 10.1021/acs.jmedchem.3c02094. Epub 2024 Feb 1. J Med Chem. 2024. PMID: 38301029
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease.
De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A. De Simone A, et al. Among authors: russomanno p. ACS Med Chem Lett. 2019 Feb 4;10(4):469-474. doi: 10.1021/acsmedchemlett.8b00507. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996781 Free PMC article.
New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function.
Saviano A, Manosour AA, Raucci F, Merlino F, Marigliano N, Schettino A, Wahid M, Begum J, Filer A, Manning JE, Casillo GM, Piccolo M, Ferraro MG, Marzano S, Russomanno P, Bellavita R, Irace C, Amato J, Alfaifi M, Rimmer P, Iqbal T, Pieretti S, Vellecco V, Caso F, Costa L, Giacomelli R, Scarpa R, Cirino G, Bucci M, McGettrick HM, Grieco P, Iqbal AJ, Maione F. Saviano A, et al. Among authors: russomanno p. Ann Rheum Dis. 2023 Nov;82(11):1415-1428. doi: 10.1136/ard-2023-224479. Epub 2023 Aug 14. Ann Rheum Dis. 2023. PMID: 37580108 Free PMC article.
13 results