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Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.
Nobs SP, Kolodziejczyk AA, Adler L, Horesh N, Botscharnikow C, Herzog E, Mohapatra G, Hejndorf S, Hodgetts RJ, Spivak I, Schorr L, Fluhr L, Kviatcovsky D, Zacharia A, Njuki S, Barasch D, Stettner N, Dori-Bachash M, Harmelin A, Brandis A, Mehlman T, Erez A, He Y, Ferrini S, Puschhof J, Shapiro H, Kopf M, Moussaieff A, Abdeen SK, Elinav E. Nobs SP, et al. Among authors: mehlman t. Nature. 2023 Dec;624(7992):645-652. doi: 10.1038/s41586-023-06803-0. Epub 2023 Dec 13. Nature. 2023. PMID: 38093014 Free PMC article.
N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer's disease mouse model.
Suzzi S, Croese T, Ravid A, Gold O, Clark AR, Medina S, Kitsberg D, Adam M, Vernon KA, Kohnert E, Shapira I, Malitsky S, Itkin M, Brandis A, Mehlman T, Salame TM, Colaiuta SP, Cahalon L, Slyper M, Greka A, Habib N, Schwartz M. Suzzi S, et al. Among authors: mehlman t. Nat Commun. 2023 Mar 9;14(1):1293. doi: 10.1038/s41467-023-36759-8. Nat Commun. 2023. PMID: 36894557 Free PMC article.
The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.
Stroganov S, Harris T, Fellus-Alyagor L, Ben Moyal L, Plitman Mayo R, Golani O, Hirsch D, Ben-Dor S, Brandis A, Mehlman T, Kovo M, Biron-Shental T, Dekel N, Neeman M. Stroganov S, et al. Among authors: mehlman t. Elife. 2024 Feb 5;13:e82631. doi: 10.7554/eLife.82631. Elife. 2024. PMID: 38314803 Free PMC article.
Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Duncan-Lowey B, Tal N, Johnson AG, Rawson S, Mayer ML, Doron S, Millman A, Melamed S, Fedorenko T, Kacen A, Brandis A, Mehlman T, Amitai G, Sorek R, Kranzusch PJ. Duncan-Lowey B, et al. Among authors: mehlman t. Cell. 2023 Mar 2;186(5):987-998.e15. doi: 10.1016/j.cell.2023.01.012. Epub 2023 Feb 9. Cell. 2023. PMID: 36764290 Free PMC article.
Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.
Lee AA, Amick I, Aschenbrenner JC, Barr HM, Benjamin J, Brandis A, Cohen G, Diaz-Tapia R, Duberstein S, Dixon J, Cousins D, Fairhead M, Fearon D, Frick J, Gayvert J, Godoy AS, Griffin EJ, Huber K, Koekemoer L, Lahav N, Marples PG, McGovern BL, Mehlman T, Robinson MC, Singh U, Szommer T, Tomlinson CWE, Vargo T, von Delft F, Wang S, White K, Williams E, Winokan M. Lee AA, et al. Among authors: mehlman t. bioRxiv [Preprint]. 2024 Aug 21:2024.08.19.608619. doi: 10.1101/2024.08.19.608619. bioRxiv. 2024. PMID: 39229055 Free PMC article. Preprint.
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