Sasaguri H - Search Results

1

Cystatin F (Cst7) drives sex-dependent changes in microglia in an amyloid-driven model of Alzheimer's disease.

Daniels MJD, Lefevre L, Szymkowiak S, Drake A, McCulloch L, Tzioras M, Barrington J, Dando OR, He X, Mohammad M, Sasaguri H, Saito T, Saido TC, Spires-Jones TL, McColl BW. Daniels MJD, et al. Among authors: sasaguri h. Elife. 2023 Dec 12;12:e85279. doi: 10.7554/eLife.85279. Elife. 2023. PMID: 38085657 Free PMC article.

2

Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.

Hashimoto S, Matsuba Y, Takahashi M, Kamano N, Watamura N, Sasaguri H, Takado Y, Yoshihara Y, Saito T, Saido TC. Hashimoto S, et al. Among authors: sasaguri h. Sci Rep. 2023 Jan 20;13(1):1109. doi: 10.1038/s41598-023-27653-w. Sci Rep. 2023. PMID: 36670138 Free PMC article.

3

A fully automated home cage for long-term continuous phenotyping of mouse cognition and behavior.

Ho H, Kejzar N, Sasaguri H, Saito T, Saido TC, De Strooper B, Bauza M, Krupic J. Ho H, et al. Among authors: sasaguri h. Cell Rep Methods. 2023 Jul 13;3(7):100532. doi: 10.1016/j.crmeth.2023.100532. eCollection 2023 Jul 24. Cell Rep Methods. 2023. PMID: 37533650 Free PMC article.

4

Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice.

Wieg L, Ciola JC, Wasén CC, Gaba F, Colletti BR, Schroeder MK, Hinshaw RG, Ekwudo MN, Holtzman DM, Saito T, Sasaguri H, Saido TC, Cox LM, Lemere CA. Wieg L, et al. Among authors: sasaguri h. Int J Mol Sci. 2024 Aug 29;25(17):9379. doi: 10.3390/ijms25179379. Int J Mol Sci. 2024. PMID: 39273325 Free PMC article.

5

The Icelandic Mutation (APP-A673T) Is Protective against Amyloid Pathology In Vivo.

Shimohama S, Fujioka R, Mihira N, Sekiguchi M, Sartori L, Joho D, Saito T, Saido TC, Nakahara J, Hino T, Hoshino A, Sasaguri H. Shimohama S, et al. Among authors: sasaguri h. J Neurosci. 2024 Nov 20;44(47):e0223242024. doi: 10.1523/JNEUROSCI.0223-24.2024. J Neurosci. 2024. PMID: 39496485

6

Introduction of Genetic Mutations Into Mice by Base Editor and Target-AID.

Sasaguri H. Sasaguri H. Methods Mol Biol. 2023;2637:111-124. doi: 10.1007/978-1-0716-3016-7_9. Methods Mol Biol. 2023. PMID: 36773142

7

Use of the Representative Base Editing Tool Target-AID to Introduce Pathogenic Mutations into Mice.

Sasaguri H. Sasaguri H. Methods Mol Biol. 2023;2606:87-97. doi: 10.1007/978-1-0716-2879-9_8. Methods Mol Biol. 2023. PMID: 36592310

8

Tau accumulation induces microglial state alterations in Alzheimer's disease model mice.

Nagata K, Hashimoto S, Joho D, Fujioka R, Matsuba Y, Sekiguchi M, Mihira N, Motooka D, Liu YC, Okuzaki D, Kikuchi M, Murayama S, Saido TC, Kiyama H, Sasaguri H. Nagata K, et al. Among authors: sasaguri h. eNeuro. 2024 Nov 26:ENEURO.0260-24.2024. doi: 10.1523/ENEURO.0260-24.2024. Online ahead of print. eNeuro. 2024. PMID: 39592224 Free article.

9

Metabolic resistance of Aβ3pE-42, a target epitope of the anti-Alzheimer therapeutic antibody, donanemab.

Iwata N, Tsubuki S, Sekiguchi M, Watanabe-Iwata K, Matsuba Y, Kamano N, Fujioka R, Takamura R, Watamura N, Kakiya N, Mihira N, Morito T, Shirotani K, Mann DM, Robinson AC, Hashimoto S, Sasaguri H, Saito T, Higuchi M, Saido TC. Iwata N, et al. Among authors: sasaguri h. Life Sci Alliance. 2024 Sep 30;7(12):e202402650. doi: 10.26508/lsa.202402650. Print 2024 Dec. Life Sci Alliance. 2024. PMID: 39348937 Free PMC article.

10

Production of a heterozygous exon skipping model of common marmosets using gene-editing technology.

Sato K, Sasaguri H, Kumita W, Sakuma T, Morioka T, Nagata K, Inoue T, Kurotaki Y, Mihira N, Tagami M, Manabe RI, Ozaki K, Okazaki Y, Yamamoto T, Suematsu M, Saido TC, Sasaki E. Sato K, et al. Among authors: sasaguri h. Lab Anim (NY). 2024 Sep;53(9):244-251. doi: 10.1038/s41684-024-01424-0. Epub 2024 Aug 30. Lab Anim (NY). 2024. PMID: 39215182 Free PMC article.

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