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Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.
Humphrey J, Brophy E, Kosoy R, Zeng B, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, Münch A, Kitata RB, Kleopoulos SP, Argyriou S, Shao Z, Francoeur N, Tsai CF, Gritsenko MA, Monroe ME, Paurus VL, Weitz KK, Shi T, Sebra R, Liu T, de Witte LD, Goate AM, Bennett DA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P, Raj T. Humphrey J, et al. Among authors: mattei d. medRxiv [Preprint]. 2023 Dec 1:2023.12.01.23299073. doi: 10.1101/2023.12.01.23299073. medRxiv. 2023. PMID: 38076956 Free PMC article. Preprint.
A microglia-containing cerebral organoid model to study early life immune challenges.
Buonfiglioli A, Kübler R, Missall R, De Jong R, Chan S, Haage V, Wendt S, Lin AJ, Mattei D, Graziani M, Latour B, Gigase F, Nygaard HB, De Jager PL, De Witte LD. Buonfiglioli A, et al. Among authors: mattei d. bioRxiv [Preprint]. 2024 May 29:2024.05.24.595814. doi: 10.1101/2024.05.24.595814. bioRxiv. 2024. Update in: Brain Behav Immun. 2024 Nov 3;123:1127-1146. doi: 10.1016/j.bbi.2024.11.008. PMID: 38826204 Free PMC article. Updated. Preprint.
Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter SM, von Arx AS, Cruz-Ochoa N, Dawson K, Ivanov A, Mueller FS, Lin HY, Amport R, Mildenberger W, Mattei D, Beule D, Földy C, Greter M, Notter T, Meyer U. Schalbetter SM, et al. Among authors: mattei d. Sci Adv. 2022 Mar 4;8(9):eabi6672. doi: 10.1126/sciadv.abi6672. Epub 2022 Mar 2. Sci Adv. 2022. PMID: 35235358 Free PMC article.
Neuronal activity increases translocator protein (TSPO) levels.
Notter T, Schalbetter SM, Clifton NE, Mattei D, Richetto J, Thomas K, Meyer U, Hall J. Notter T, et al. Among authors: mattei d. Mol Psychiatry. 2021 Jun;26(6):2025-2037. doi: 10.1038/s41380-020-0745-1. Epub 2020 May 12. Mol Psychiatry. 2021. PMID: 32398717 Free PMC article.
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Rodríguez de Los Santos M, Rivalan M, David FS, Stumpf A, Pitsch J, Tsortouktzidis D, Velasquez LM, Voigt A, Schilling K, Mattei D, Long M, Vogt G, Knaus A, Fischer-Zirnsak B, Wittler L, Timmermann B, Robinson PN, Horn D, Mundlos S, Kornak U, Becker AJ, Schmitz D, Winter Y, Krawitz PM. Rodríguez de Los Santos M, et al. Among authors: mattei d. Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2014481118. doi: 10.1073/pnas.2014481118. Proc Natl Acad Sci U S A. 2021. PMID: 33402532 Free PMC article.
159 results