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Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.
Humphrey J, Brophy E, Kosoy R, Zeng B, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, Münch A, Kitata RB, Kleopoulos SP, Argyriou S, Shao Z, Francoeur N, Tsai CF, Gritsenko MA, Monroe ME, Paurus VL, Weitz KK, Shi T, Sebra R, Liu T, de Witte LD, Goate AM, Bennett DA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P, Raj T. Humphrey J, et al. Among authors: munch a. medRxiv [Preprint]. 2023 Dec 1:2023.12.01.23299073. doi: 10.1101/2023.12.01.23299073. medRxiv. 2023. PMID: 38076956 Free PMC article. Preprint.
Normal aging induces A1-like astrocyte reactivity.
Clarke LE, Liddelow SA, Chakraborty C, Münch AE, Heiman M, Barres BA. Clarke LE, et al. Among authors: munch ae. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1896-E1905. doi: 10.1073/pnas.1800165115. Epub 2018 Feb 7. Proc Natl Acad Sci U S A. 2018. PMID: 29437957 Free PMC article.
Neurotoxic reactive astrocytes are induced by activated microglia.
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Liddelow SA, et al. Among authors: munch ae. Nature. 2017 Jan 26;541(7638):481-487. doi: 10.1038/nature21029. Epub 2017 Jan 18. Nature. 2017. PMID: 28099414 Free PMC article.
Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Guttenplan KA, Weigel MK, Prakash P, Wijewardhane PR, Hasel P, Rufen-Blanchette U, Münch AE, Blum JA, Fine J, Neal MC, Bruce KD, Gitler AD, Chopra G, Liddelow SA, Barres BA. Guttenplan KA, et al. Among authors: munch ae. Nature. 2021 Nov;599(7883):102-107. doi: 10.1038/s41586-021-03960-y. Epub 2021 Oct 6. Nature. 2021. PMID: 34616039
Update on the Epidemiology and Management of Microscopic Colitis.
Peery AF, Khalili H, Münch A, Pardi DS. Peery AF, et al. Among authors: munch a. Clin Gastroenterol Hepatol. 2024 Sep 11:S1542-3565(24)00823-1. doi: 10.1016/j.cgh.2024.08.026. Online ahead of print. Clin Gastroenterol Hepatol. 2024. PMID: 39270919 Review.
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development.
Kantarci H, Elvira PD, Thottumkara AP, O'Connell EM, Iyer M, Donovan LJ, Dugan MQ, Ambiel N, Granados A, Zeng H, Saw NL, Brosius Lutz A, Sloan SA, Gray EE, Tran KV, Vichare A, Yeh AK, Münch AE, Huber M, Agrawal A, Morri M, Zhong H, Shamloo M, Anderson TA, Tawfik VL, Du Bois J, Zuchero JB. Kantarci H, et al. Among authors: munch ae. Cell. 2024 Aug 22;187(17):4690-4712.e30. doi: 10.1016/j.cell.2024.07.033. Epub 2024 Aug 13. Cell. 2024. PMID: 39142281
LRRK2 G2019S variant is associated with transcriptional changes in Parkinson's disease human myeloid cells under proinflammatory environment.
Navarro E, Efthymiou AG, Parks M, Riboldi GM, Vialle RA, Udine E, Muller BZ, Humphrey J, Allan A, Argyrou CC, Lopes KP, Münch A, Raymond D, Sachdev R, Shanker VL, Miravite J, Katsnelson V, Leaver K, Frucht S, Bressman SB, Marcora E, Saunders-Pullman R, Goate A, Raj T. Navarro E, et al. Among authors: munch a. bioRxiv [Preprint]. 2024 May 31:2024.05.27.594821. doi: 10.1101/2024.05.27.594821. bioRxiv. 2024. PMID: 38854101 Free PMC article. Preprint.
159 results