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Wnt/β-Catenin-Signaling Modulates Megakaryopoiesis at the Megakaryocyte-Erythrocyte Progenitor Stage in the Hematopoietic System.
Yalcin BH, Macas J, Wiercinska E, Harter PN, Fawaz M, Schmachtel T, Ghiro I, Bieniek E, Kosanovic D, Thom S, Fruttiger M, Taketo MM, Schermuly RT, Rieger MA, Plate KH, Bonig H, Liebner S. Yalcin BH, et al. Among authors: schmachtel t. Cells. 2023 Dec 4;12(23):2765. doi: 10.3390/cells12232765. Cells. 2023. PMID: 38067194 Free PMC article.
The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome.
Külp M, Larghero P, Alten J, Cario G, Eckert C, Caye-Eude A, Cavé H, Schmachtel T, Bardini M, Cazzaniga G, De Lorenzo P, Valsecchi MG, Bonig H, Meyer C, Rieger MA, Marschalek R. Külp M, et al. Among authors: schmachtel t. Leukemia. 2023 Jun;37(6):1216-1233. doi: 10.1038/s41375-023-01895-z. Epub 2023 Apr 26. Leukemia. 2023. PMID: 37100882 Free PMC article.
RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions.
Weiss LM, Warwick T, Zehr S, Günther S, Wolf S, Schmachtel T, Izquierdo Ponce J, Pálfi K, Teichmann T, Schneider A, Stötzel J, Knapp S, Weigert A, Savai R, Rieger MA, Oellerich T, Wittig I, Oo JA, Brandes RP, Leisegang MS. Weiss LM, et al. Among authors: schmachtel t. Commun Biol. 2024 Sep 13;7(1):1131. doi: 10.1038/s42003-024-06794-2. Commun Biol. 2024. PMID: 39271940 Free PMC article.
Development of a Potent and Selective G2A (GPR132) Agonist.
Hernandez-Olmos V, Heering J, Marinescu B, Schermeng T, Ivanov VV, Moroz YS, Nevermann S, Mathes M, Ehrler JHM, Alnouri MW, Wolf M, Haydo AS, Schmachtel T, Zaliani A, Höfner G, Kaiser A, Schubert-Zsilavecz M, Beck-Sickinger AG, Offermanns S, Gribbon P, Rieger MA, Merk D, Sisignano M, Steinhilber D, Proschak E. Hernandez-Olmos V, et al. Among authors: schmachtel t. J Med Chem. 2024 Jul 11;67(13):10567-10588. doi: 10.1021/acs.jmedchem.3c02164. Epub 2024 Jun 25. J Med Chem. 2024. PMID: 38917049
Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice.
Müller S, Wedler A, Breuer J, Glaß M, Bley N, Lederer M, Haase J, Misiak C, Fuchs T, Ottmann A, Schmachtel T, Shalamova L, Ewe A, Aigner A, Rossbach O, Hüttelmaier S. Müller S, et al. Among authors: schmachtel t. NAR Cancer. 2020 Jul 31;2(3):zcaa014. doi: 10.1093/narcan/zcaa014. eCollection 2020 Sep. NAR Cancer. 2020. PMID: 34316687 Free PMC article.