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SON is an essential m6A target for hematopoietic stem cell fate.
Luo H, Cortés-López M, Tam CL, Xiao M, Wakiro I, Chu KL, Pierson A, Chan M, Chang K, Yang X, Fecko D, Han G, Ahn EE, Morris QD, Landau DA, Kharas MG. Luo H, et al. Among authors: yang x. Cell Stem Cell. 2023 Dec 7;30(12):1658-1673.e10. doi: 10.1016/j.stem.2023.11.006. Cell Stem Cell. 2023. PMID: 38065069
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells.
Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu EL, Joshi S, Barin E, Schurer A, Chan M, Chang K, Han GYQ, Pierson AJ, Xiao M, Yang X, Kuehm LM, Hong Y, Nguyen DTT, Chiosis G, Kentsis A, Leslie C, Vu LP, Kharas MG. Herrejon Chavez F, et al. Among authors: yang x. Nat Commun. 2023 Apr 21;14(1):2290. doi: 10.1038/s41467-023-38001-x. Nat Commun. 2023. PMID: 37085479 Free PMC article.
Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target.
Palacios F, Yan XJ, Ferrer G, Chen SS, Vergani S, Yang X, Gardner J, Barrientos JC, Rock P, Burack R, Kolitz JE, Allen SL, Kharas MG, Abdel-Wahab O, Rai KR, Chiorazzi N. Palacios F, et al. Among authors: yang x. Leukemia. 2021 Apr;35(4):1037-1052. doi: 10.1038/s41375-020-01115-y. Epub 2021 Jan 27. Leukemia. 2021. PMID: 33504942 Free PMC article.
TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma.
Erazo T, Evans CM, Zakheim D, Chu EL, Refermat AY, Asgari Z, Yang X, Da Silva Ferreira M, Mehta S, Russo MV, Knezevic A, Zhang XP, Chen Z, Fennell M, Garippa R, Seshan V, de Stanchina E, Barbash O, Batlevi CL, Leslie CS, Melnick AM, Younes A, Kharas MG. Erazo T, et al. Among authors: yang x. Nat Commun. 2022 Sep 27;13(1):5676. doi: 10.1038/s41467-022-33137-8. Nat Commun. 2022. PMID: 36167829 Free PMC article.
Identification of functional cooperative mutations of SETD2 in human acute leukemia.
Zhu X, He F, Zeng H, Ling S, Chen A, Wang Y, Yan X, Wei W, Pang Y, Cheng H, Hua C, Zhang Y, Yang X, Lu X, Cao L, Hao L, Dong L, Zou W, Wu J, Li X, Zheng S, Yan J, Zhou J, Zhang L, Mi S, Wang X, Zhang L, Zou Y, Chen Y, Geng Z, Wang J, Zhou J, Liu X, Wang J, Yuan W, Huang G, Cheng T, Wang QF. Zhu X, et al. Among authors: yang x. Nat Genet. 2014 Mar;46(3):287-93. doi: 10.1038/ng.2894. Epub 2014 Feb 9. Nat Genet. 2014. PMID: 24509477 Free PMC article.
73,864 results
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