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Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency.
J Med Chem. 2023 Dec 28;66(24):16762-16771. doi: 10.1021/acs.jmedchem.3c01435. Epub 2023 Dec 8.
J Med Chem. 2023.
PMID: 38064686
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties.
Lewandowski M, Carmina M, Knümann L, Sai M, Willems S, Kasch T, Pollinger J, Knapp S, Marschner JA, Chaikuad A, Merk D.
Lewandowski M, et al. Among authors: knumann l.
J Med Chem. 2024 Feb 8;67(3):2152-2164. doi: 10.1021/acs.jmedchem.3c02095. Epub 2024 Jan 18.
J Med Chem. 2024.
PMID: 38237049
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