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Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion.
Crozier TWM, Greenwood EJD, Williamson JC, Guo W, Porter LM, Gabaev I, Teixeira-Silva A, Grice GL, Wickenhagen A, Stanton RJ, Wang ECY, Wilson SJ, Matheson NJ, Nathan JA, McCaughan F, Lehner PJ. Crozier TWM, et al. Among authors: guo w. Wellcome Open Res. 2022 Sep 7;7:224. doi: 10.12688/wellcomeopenres.17946.1. eCollection 2022. Wellcome Open Res. 2022. PMID: 36483314 Free PMC article.
Cigarette smoke preferentially induces full length ACE2 expression in differentiated primary human airway cultures but does not alter the efficiency of cellular SARS-CoV-2 infection.
Porter LM, Guo W, Crozier TW, Greenwood EJ, Ortmann B, Kottmann D, Nathan JA, Mahadeva R, Lehner PJ, McCaughan F. Porter LM, et al. Among authors: guo w. Heliyon. 2023 Mar;9(3):e14383. doi: 10.1016/j.heliyon.2023.e14383. Epub 2023 Mar 11. Heliyon. 2023. PMID: 36938474 Free PMC article.
In vitro platform to model the function of ionocytes in the human airway epithelium.
Vilà-González M, Pinte L, Fradique R, Causa E, Kool H, Rodrat M, Morell CM, Al-Thani M, Porter L, Guo W, Maeshima R, Hart SL, McCaughan F, Granata A, Sheppard DN, Floto RA, Rawlins EL, Cicuta P, Vallier L. Vilà-González M, et al. Among authors: guo w. Respir Res. 2024 Apr 25;25(1):180. doi: 10.1186/s12931-024-02800-7. Respir Res. 2024. PMID: 38664797 Free PMC article.
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