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Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE and photoreceptors in wet vs. dry age-related macular degeneration.
Babapoor-Farrokhran S, Qin Y, Flores-Bellver M, Niu Y, Bhutto IA, Aparicio-Domingo S, Guo C, Rodrigues M, Domashevich T, Deshpande M, Megarity H, Chopde R, Eberhart CG, Canto-Soler V, Montaner S, Sodhi A. Babapoor-Farrokhran S, et al. Among authors: deshpande m. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2302845120. doi: 10.1073/pnas.2302845120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055741 Free PMC article.
HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye disease.
Guo C, Deshpande M, Niu Y, Kachwala I, Flores-Bellver M, Megarity H, Nuse T, Babapoor-Farrokhran S, Ramada M, Sanchez J, Inamdar N, Johnson TV, Canto-Soler MV, Montaner S, Sodhi A. Guo C, et al. Among authors: deshpande m. Cell Rep. 2023 Jan 31;42(1):111976. doi: 10.1016/j.celrep.2022.111976. Epub 2023 Jan 10. Cell Rep. 2023. PMID: 36640318 Free PMC article.
Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.
Zhang J, Sharma D, Dinabandhu A, Sanchez J, Applewhite B, Jee K, Deshpande M, Flores-Bellver M, Hu MW, Guo C, Salman S, Hwang Y, Anders NM, Rudek MA, Qian J, Canto-Soler MV, Semenza GL, Montaner S, Sodhi A. Zhang J, et al. Among authors: deshpande m. J Clin Invest. 2023 Jul 3;133(13):e163290. doi: 10.1172/JCI163290. J Clin Invest. 2023. PMID: 37227777 Free PMC article.
Targeted proteomics of cerebrospinal fluid in treatment naïve multiple sclerosis patients identifies immune biomarkers of clinical phenotypes.
Rabin A, Bello E, Kumar S, Zeki DA, Afshari K, Deshpande M, Francis N, Khalighinejad F, Umeton R, Radu I, Qutab F, Kwong D, Kurban M, Hemond C, Richmond JM, Ionete C. Rabin A, et al. Among authors: deshpande m. Sci Rep. 2024 Sep 18;14(1):21793. doi: 10.1038/s41598-024-67769-1. Sci Rep. 2024. PMID: 39294186 Free PMC article.
536 results