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Page 1
Factor VIII trafficking to CD4+ T cells shapes its immunogenicity and requires several types of antigen-presenting cells.
Kaczmarek R, Piñeros AR, Patterson PE, Bertolini TB, Perrin GQ, Sherman A, Born J, Arisa S, Arvin MC, Kamocka MM, Martinez MM, Dunn KW, Quinn SM, Morris JJ, Wilhelm AR, Kaisho T, Munoz-Melero M, Biswas M, Kaplan MH, Linnemann AK, George LA, Camire RM, Herzog RW. Kaczmarek R, et al. Among authors: pineros ar. Blood. 2023 Jul 20;142(3):290-305. doi: 10.1182/blood.2022018937. Blood. 2023. PMID: 37192286 Free PMC article.
IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice.
Butterfield JSS, Yamada K, Bertolini TB, Syed F, Kumar SRP, Li X, Arisa S, Piñeros AR, Tapia A, Rogers CA, Li N, Rana J, Biswas M, Terhorst C, Kaufman RJ, de Jong YP, Herzog RW. Butterfield JSS, et al. Among authors: pineros ar. Mol Ther. 2022 Dec 7;30(12):3552-3569. doi: 10.1016/j.ymthe.2022.07.005. Epub 2022 Jul 12. Mol Ther. 2022. PMID: 35821634 Free PMC article.
Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype.
Anderson-Baucum E, Piñeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RG. Anderson-Baucum E, et al. Among authors: pineros ar. Cell Metab. 2021 Sep 7;33(9):1883-1893.e7. doi: 10.1016/j.cmet.2021.08.003. Cell Metab. 2021. PMID: 34496231 Free PMC article.
Sepsis expands a CD39+ plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity.
Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, Kauffenstein G, Nakaya HI, Borges MC, Zamboni DS, Fonseca DM, Paschoal JAR, Cunha TM, Quesniaux V, Linden J, Cunha FQ, Ryffel B, Alves-Filho JC. Nascimento DC, et al. Among authors: pineros ar. Immunity. 2021 Sep 14;54(9):2024-2041.e8. doi: 10.1016/j.immuni.2021.08.005. Epub 2021 Sep 1. Immunity. 2021. PMID: 34473957 Free article.
21 results