Kumar SRP - Search Results

1

TLR9-independent CD8⁺ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.

Kumar SRP, Biswas M, Cao D, Arisa S, Muñoz-Melero M, Lam AK, Piñeros AR, Kapur R, Kaisho T, Kaufman RJ, Xiao W, Shayakhmetov DM, Terhorst C, de Jong YP, Herzog RW. Kumar SRP, et al. Mol Ther. 2024 Feb 7;32(2):325-339. doi: 10.1016/j.ymthe.2023.11.029. Epub 2023 Dec 5. Mol Ther. 2024. PMID: 38053332 Free article.

2

Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg.

Biswas M, Sarkar D, Kumar SR, Nayak S, Rogers GL, Markusic DM, Liao G, Terhorst C, Herzog RW. Biswas M, et al. Blood. 2015 May 7;125(19):2937-47. doi: 10.1182/blood-2014-09-599266. Epub 2015 Apr 1. Blood. 2015. PMID: 25833958 Free PMC article.

3

Clinical development of gene therapy: results and lessons from recent successes.

Kumar SR, Markusic DM, Biswas M, High KA, Herzog RW. Kumar SR, et al. Mol Ther Methods Clin Dev. 2016 May 25;3:16034. doi: 10.1038/mtm.2016.34. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27257611 Free PMC article. Review.

4

The Balance between CD8⁺ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.

Kumar SRP, Hoffman BE, Terhorst C, de Jong YP, Herzog RW. Kumar SRP, et al. Mol Ther. 2017 Apr 5;25(4):880-891. doi: 10.1016/j.ymthe.2017.02.014. Epub 2017 Mar 9. Mol Ther. 2017. PMID: 28284982 Free PMC article.

5

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8⁺ T cells.

Rogers GL, Shirley JL, Zolotukhin I, Kumar SRP, Sherman A, Perrin GQ, Hoffman BE, Srivastava A, Basner-Tschakarjan E, Wallet MA, Terhorst C, Biswas M, Herzog RW. Rogers GL, et al. Among authors: kumar srp. Blood. 2017 Jun 15;129(24):3184-3195. doi: 10.1182/blood-2016-11-751040. Epub 2017 May 3. Blood. 2017. PMID: 28468798 Free PMC article.

6

Immune Modulatory Cell Therapy for Hemophilia B Based on CD20-Targeted Lentiviral Gene Transfer to Primary B Cells.

Wang X, Herzog RW, Byrne BJ, Kumar SRP, Zhou Q, Buchholz CJ, Biswas M. Wang X, et al. Among authors: kumar srp. Mol Ther Methods Clin Dev. 2017 Mar 29;5:76-82. doi: 10.1016/j.omtm.2017.03.005. eCollection 2017 Jun 16. Mol Ther Methods Clin Dev. 2017. PMID: 28480307 Free PMC article.

7

Gene Therapy With Regulatory T Cells: A Beneficial Alliance.

Biswas M, Kumar SRP, Terhorst C, Herzog RW. Biswas M, et al. Among authors: kumar srp. Front Immunol. 2018 Mar 19;9:554. doi: 10.3389/fimmu.2018.00554. eCollection 2018. Front Immunol. 2018. PMID: 29616042 Free PMC article. Review.

8

TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer.

Butterfield JSS, Biswas M, Shirley JL, Kumar SRP, Sherman A, Terhorst C, Ling C, Herzog RW. Butterfield JSS, et al. Among authors: kumar srp. Hum Gene Ther Methods. 2019 Jun;30(3):81-92. doi: 10.1089/hgtb.2019.013. Hum Gene Ther Methods. 2019. PMID: 31140323 Free PMC article.

9

Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia.

Kumar SRP, Wang X, Avuthu N, Bertolini TB, Terhorst C, Guda C, Daniell H, Herzog RW. Kumar SRP, et al. Front Immunol. 2020 May 20;11:844. doi: 10.3389/fimmu.2020.00844. eCollection 2020. Front Immunol. 2020. PMID: 32508814 Free PMC article.

10

B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin.

Biswas M, Palaschak B, Kumar SRP, Rana J, Markusic DM. Biswas M, et al. Among authors: kumar srp. Front Immunol. 2020 Jun 24;11:1293. doi: 10.3389/fimmu.2020.01293. eCollection 2020. Front Immunol. 2020. PMID: 32670285 Free PMC article.

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