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Page 1
Oncogenic drivers dictate immune control of acute myeloid leukemia.
Austin RJ, Straube J, Halder R, Janardhanan Y, Bruedigam C, Witkowski M, Cooper L, Porter A, Braun M, Souza-Fonseca-Guimaraes F, Minnie SA, Cooper E, Jacquelin S, Song A, Bald T, Nakamura K, Hill GR, Aifantis I, Lane SW, Bywater MJ. Austin RJ, et al. Nat Commun. 2023 Apr 14;14(1):2155. doi: 10.1038/s41467-023-37592-9. Nat Commun. 2023. PMID: 37059710 Free PMC article.
Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer.
Poursani EM, Mercatelli D, Raninga P, Bell JL, Saletta F, Kohane FV, Neumann DP, Zheng Y, Rouaen JRC, Jue TR, Michniewicz FT, Schadel P, Kasiou E, Tsoli M, Cirillo G, Waters S, Shai-Hee T, Cazzoli R, Brettle M, Slapetova I, Kasherman M, Whan R, Souza-Fonseca-Guimaraes F, Vahdat L, Ziegler D, Lock JG, Giorgi FM, Khanna K, Vittorio O. Poursani EM, et al. Cell Biosci. 2023 Jul 21;13(1):132. doi: 10.1186/s13578-023-01083-7. Cell Biosci. 2023. PMID: 37480151 Free PMC article.
Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation.
McCulloch TR, Rossi GR, Alim L, Lam PY, Wong JKM, Coleborn E, Kumari S, Keane C, Kueh AJ, Herold MJ, Wilhelm C, Knolle PA, Kane L, Wells TJ, Souza-Fonseca-Guimaraes F. McCulloch TR, et al. Among authors: souza fonseca guimaraes f. Nat Commun. 2024 Nov 14;15(1):9871. doi: 10.1038/s41467-024-54232-y. Nat Commun. 2024. PMID: 39543125 Free PMC article.
A scalable, spin-free approach to generate enhanced induced pluripotent stem cell-derived natural killer cells for cancer immunotherapy.
Rossi GR, Sun J, Lin CY, Wong JK, Alim L, Lam PY, Khosrotehrani K, Wolvetang E, Cheetham SW, Derrick EB, Amoako A, Lehner C, Brooks AJ, Beavis PA, Souza-Fonseca-Guimaraes F. Rossi GR, et al. Among authors: souza fonseca guimaraes f. Immunol Cell Biol. 2024 Nov;102(10):924-934. doi: 10.1111/imcb.12820. Epub 2024 Sep 13. Immunol Cell Biol. 2024. PMID: 39269338
NK cell heparanase controls tumor invasion and immune surveillance.
Putz EM, Mayfosh AJ, Kos K, Barkauskas DS, Nakamura K, Town L, Goodall KJ, Yee DY, Poon IK, Baschuk N, Souza-Fonseca-Guimaraes F, Hulett MD, Smyth MJ. Putz EM, et al. Among authors: souza fonseca guimaraes f. J Clin Invest. 2024 Jul 1;134(13):e183295. doi: 10.1172/JCI183295. J Clin Invest. 2024. PMID: 38949030 Free PMC article. No abstract available.
The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy.
McCulloch TR, Rossi GR, Miranda-Hernandez S, Valencia-Hernandez AM, Alim L, Belle CJ, Krause A, Zacchi LF, Lam PY, Nakamura K, Kupz A, Wells TJ, Souza-Fonseca-Guimaraes F. McCulloch TR, et al. Among authors: souza fonseca guimaraes f. Immunol Cell Biol. 2024 Sep;102(8):721-733. doi: 10.1111/imcb.12794. Epub 2024 Jun 14. Immunol Cell Biol. 2024. PMID: 38873699
94 results