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Selective and brain-penetrant HCN1 inhibitors reveal links between synaptic integration, cortical function, and working memory.
Harde E, Hierl M, Weber M, Waiz D, Wyler R, Wach JY, Haab R, Gundlfinger A, He W, Schnider P, Paina M, Rolland JF, Greiter-Wilke A, Gasser R, Reutlinger M, Dupont A, Roberts S, O'Connor EC, Bartels B, Hall BJ. Harde E, et al. Among authors: he w. Cell Chem Biol. 2024 Mar 21;31(3):577-592.e23. doi: 10.1016/j.chembiol.2023.11.004. Epub 2023 Dec 1. Cell Chem Biol. 2024. PMID: 38042151 Free article.
Discovery of Orally Available and Brain Penetrant AEP Inhibitors.
Krummenacher D, He W, Kuhn B, Schnider C, Beurier A, Brom V, Sivasothy T, Marty C, Tosstorff A, Hewings DS, Mesch S, Pinard E, Brändlin M, Hochstrasser R, Westwood P, Rothe J, Kronenberger A, Morandi F, Gutbier S, Schuler A, Heer D, Gloria LE, Joedicke L, Rudolph MG, Müller L, Grüninger F, Baumann K, Kaniyappan S, Manevski N, Bartels B. Krummenacher D, et al. Among authors: he w. J Med Chem. 2023 Dec 28;66(24):17026-17043. doi: 10.1021/acs.jmedchem.3c01804. Epub 2023 Dec 13. J Med Chem. 2023. PMID: 38090813
A diffusion tensor imaging-based multidimensional study of brain structural changes after long-term high-altitude exposure and their relationships with cognitive function.
Liu N, Feng L, Chai S, Li H, He Y, Guo Y, Hu X, Li H, Li X, Zhou Z, Li X, Huang Y, He W, Huang X, Wu Y, Meng J. Liu N, et al. Among authors: he w. Front Physiol. 2024 Nov 13;15:1487953. doi: 10.3389/fphys.2024.1487953. eCollection 2024. Front Physiol. 2024. PMID: 39605859 Free PMC article.
12,632 results
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