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Low-dose PLX5622 treatment prevents neuroinflammatory and neurocognitive sequelae after sepsis.
J Neuroinflammation. 2023 Dec 1;20(1):289. doi: 10.1186/s12974-023-02975-8.
J Neuroinflammation. 2023.
PMID: 38041192
Free PMC article.
Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy.
Chung HY, Wickel J, Hahn N, Mein N, Schwarzbrunn M, Koch P, Ceanga M, Haselmann H, Baade-Büttner C, von Stackelberg N, Hempel N, Schmidl L, Groth M, Andreas N, Götze J, Coldewey SM, Bauer M, Mawrin C, Dargvainiene J, Leypoldt F, Steinke S, Wang ZQ, Hust M, Geis C.
Chung HY, et al. Among authors: mein n.
Sci Adv. 2023 May 26;9(21):eabq7806. doi: 10.1126/sciadv.abq7806. Epub 2023 May 26.
Sci Adv. 2023.
PMID: 37235660
Free PMC article.
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Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain.
Wickel J, Chung HY, Ceanga M, von Stackelberg N, Hahn N, Candemir Ö, Baade-Büttner C, Mein N, Tomasini P, Woldeyesus DM, Andreas N, Baumgarten P, Koch P, Groth M, Wang ZQ, Geis C.
Wickel J, et al. Among authors: mein n.
Glia. 2024 Aug;72(8):1484-1500. doi: 10.1002/glia.24541. Epub 2024 May 23.
Glia. 2024.
PMID: 38780213
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