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SMARCB1 loss activates patient-specific distal oncogenic enhancers in malignant rhabdoid tumors.
Nat Commun. 2023 Dec 1;14(1):7762. doi: 10.1038/s41467-023-43498-3.
Nat Commun. 2023.
PMID: 38040699
Free PMC article.
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours.
Custers L, Khabirova E, Coorens THH, Oliver TRW, Calandrini C, Young MD, Vieira Braga FA, Ellis P, Mamanova L, Segers H, Maat A, Kool M, Hoving EW, van den Heuvel-Eibrink MM, Nicholson J, Straathof K, Hook L, de Krijger RR, Trayers C, Allinson K, Behjati S, Drost J.
Custers L, et al.
Nat Commun. 2021 Mar 3;12(1):1407. doi: 10.1038/s41467-021-21675-6.
Nat Commun. 2021.
PMID: 33658498
Free PMC article.
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In vitro Modeling of Embryonal Tumors.
Custers L, Paassen I, Drost J.
Custers L, et al.
Front Cell Dev Biol. 2021 Feb 26;9:640633. doi: 10.3389/fcell.2021.640633. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 33718380
Free PMC article.
Review.
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An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity.
Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, Ammerlaan C, van Ineveld RL, Derakhshan S, de Haan S, Dolman E, Lijnzaad P, Custers L, Begthel H, Kerstens HHD, Visser LL, Rookmaaker M, Verhaar M, Tytgat GAM, Kemmeren P, de Krijger RR, Al-Saadi R, Pritchard-Jones K, Kool M, Rios AC, van den Heuvel-Eibrink MM, Molenaar JJ, van Boxtel R, Holstege FCP, Clevers H, Drost J.
Calandrini C, et al. Among authors: custers l.
Nat Commun. 2020 Mar 11;11(1):1310. doi: 10.1038/s41467-020-15155-6.
Nat Commun. 2020.
PMID: 32161258
Free PMC article.
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Single cell derived mRNA signals across human kidney tumors.
Young MD, Mitchell TJ, Custers L, Margaritis T, Morales-Rodriguez F, Kwakwa K, Khabirova E, Kildisiute G, Oliver TRW, de Krijger RR, van den Heuvel-Eibrink MM, Comitani F, Piapi A, Bugallo-Blanco E, Thevanesan C, Burke C, Prigmore E, Ambridge K, Roberts K, Braga FAV, Coorens THH, Del Valle I, Wilbrey-Clark A, Mamanova L, Stewart GD, Gnanapragasam VJ, Rampling D, Sebire N, Coleman N, Hook L, Warren A, Haniffa M, Kool M, Pfister SM, Achermann JC, He X, Barker RA, Shlien A, Bayraktar OA, Teichmann SA, Holstege FC, Meyer KB, Drost J, Straathof K, Behjati S.
Young MD, et al. Among authors: custers l.
Nat Commun. 2021 Jun 23;12(1):3896. doi: 10.1038/s41467-021-23949-5.
Nat Commun. 2021.
PMID: 34162837
Free PMC article.
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Neuroblastoma and DIPG Organoid Coculture System for Personalized Assessment of Novel Anticancer Immunotherapies.
M Kholosy W, Derieppe M, van den Ham F, Ober K, Su Y, Custers L, Schild L, M J van Zogchel L, M Wellens L, R Ariese H, Szanto CL, Wienke J, Dierselhuis MP, van Vuurden D, Dolman EM, Molenaar JJ.
M Kholosy W, et al. Among authors: custers l.
J Pers Med. 2021 Aug 30;11(9):869. doi: 10.3390/jpm11090869.
J Pers Med. 2021.
PMID: 34575646
Free PMC article.
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CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.
Lopes R, Korkmaz G, Revilla SA, van Vliet R, Nagel R, Custers L, Kim Y, van Breugel PC, Zwart W, Moumbeini B, Manber Z, Elkon R, Agami R.
Lopes R, et al. Among authors: custers l.
Cancer Lett. 2018 Nov 1;436:87-95. doi: 10.1016/j.canlet.2018.08.018. Epub 2018 Aug 23.
Cancer Lett. 2018.
PMID: 30145202
Free article.
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