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Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis.
Pandey S, Vilchèze C, Werngren J, Bainomugisa A, Mansjö M, Groenheit R, Miotto P, Cirillo DM, Coulter C, Baulard AR, Schön T, Jacobs WR Jr, Djaout K, Köser CU. Pandey S, et al. Among authors: koser cu. Antimicrob Agents Chemother. 2024 Jan 10;68(1):e0109623. doi: 10.1128/aac.01096-23. Epub 2023 Dec 1. Antimicrob Agents Chemother. 2024. PMID: 38038476 Free PMC article.
Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin.
Yu X, Wang G, Chen S, Wei G, Shang Y, Dong L, Schön T, Moradigaravand D, Parkhill J, Peacock SJ, Köser CU, Huang H. Yu X, et al. Among authors: koser cu. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5232-7. doi: 10.1128/AAC.00393-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27324769 Free PMC article.
Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays.
Ajileye A, Alvarez N, Merker M, Walker TM, Akter S, Brown K, Moradigaravand D, Schön T, Andres S, Schleusener V, Omar SV, Coll F, Huang H, Diel R, Ismail N, Parkhill J, de Jong BC, Peto TE, Crook DW, Niemann S, Robledo J, Smith EG, Peacock SJ, Köser CU. Ajileye A, et al. Among authors: koser cu. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02169-16. doi: 10.1128/AAC.02169-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28137812 Free PMC article.
Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance.
Nakatani Y, Opel-Reading HK, Merker M, Machado D, Andres S, Kumar SS, Moradigaravand D, Coll F, Perdigão J, Portugal I, Schön T, Nair D, Devi KRU, Kohl TA, Beckert P, Clark TG, Maphalala G, Khumalo D, Diel R, Klaos K, Aung HL, Cook GM, Parkhill J, Peacock SJ, Swaminathan S, Viveiros M, Niemann S, Krause KL, Köser CU. Nakatani Y, et al. Among authors: koser cu. Antimicrob Agents Chemother. 2017 Nov 22;61(12):e01575-17. doi: 10.1128/AAC.01575-17. Print 2017 Dec. Antimicrob Agents Chemother. 2017. PMID: 28971867 Free PMC article.
What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis.
Heyckendorf J, Andres S, Köser CU, Olaru ID, Schön T, Sturegård E, Beckert P, Schleusener V, Kohl TA, Hillemann D, Moradigaravand D, Parkhill J, Peacock SJ, Niemann S, Lange C, Merker M. Heyckendorf J, et al. Among authors: koser cu. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01550-17. doi: 10.1128/AAC.01550-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29133554 Free PMC article.
A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.
Miotto P, Tessema B, Tagliani E, Chindelevitch L, Starks AM, Emerson C, Hanna D, Kim PS, Liwski R, Zignol M, Gilpin C, Niemann S, Denkinger CM, Fleming J, Warren RM, Crook D, Posey J, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Murray M, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, Ranganathan UDK, McNerney R, Ezewudo M, Cirillo DM, Schito M, Köser CU, Rodwell TC. Miotto P, et al. Among authors: koser cu. Eur Respir J. 2017 Dec 28;50(6):1701354. doi: 10.1183/13993003.01354-2017. Print 2017 Dec. Eur Respir J. 2017. PMID: 29284687 Free PMC article.
Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis".
Köser CU, Heyckendorf J, Andres S, Olaru ID, Schön T, Sturegård E, Beckert P, Schleusener V, Kohl TA, Hillemann D, Moradigaravand D, Parkhill J, Peacock SJ, Niemann S, Lange C, Merker M. Köser CU, et al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00616-18. doi: 10.1128/AAC.00616-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 30054377 Free PMC article. No abstract available.
d-Cycloserine Pharmacokinetics/Pharmacodynamics, Susceptibility, and Dosing Implications in Multidrug-resistant Tuberculosis: A Faustian Deal.
Deshpande D, Alffenaar JC, Köser CU, Dheda K, Chapagain ML, Simbar N, Schön T, Sturkenboom MGG, McIlleron H, Lee PS, Koeuth T, Mpagama SG, Banu S, Foongladda S, Ogarkov O, Pholwat S, Houpt ER, Heysell SK, Gumbo T. Deshpande D, et al. Among authors: koser cu. Clin Infect Dis. 2018 Nov 28;67(suppl_3):S308-S316. doi: 10.1093/cid/ciy624. Clin Infect Dis. 2018. PMID: 30496460 Free PMC article.
Standards for MIC testing that apply to the majority of bacterial pathogens should also be enforced for Mycobacterium tuberculosis complex.
Schön T, Matuschek E, Mohamed S, Utukuri M, Heysell S, Alffenaar JW, Shin S, Martinez E, Sintchenko V, Maurer FP, Keller PM, Kahlmeter G, Köser CU. Schön T, et al. Among authors: koser cu. Clin Microbiol Infect. 2019 Apr;25(4):403-405. doi: 10.1016/j.cmi.2019.01.019. Epub 2019 Feb 14. Clin Microbiol Infect. 2019. PMID: 30771527 Free PMC article. No abstract available.
77 results