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Page 1
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Luo Y, Sakaue S, Raychaudhuri S. Kang JB, et al. Among authors: rumker l. Nat Genet. 2023 Dec;55(12):2255-2268. doi: 10.1038/s41588-023-01586-6. Epub 2023 Nov 30. Nat Genet. 2023. PMID: 38036787 Free PMC article.
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, Kang JB, Rumker L, Mears J, Slowikowski K, Weinand K, Orange DE, Geraldino-Pardilla L, Deane KD, Tabechian D, Ceponis A, Firestein GS, Maybury M, Sahbudin I, Ben-Artzi A, Mandelin AM 2nd, Nerviani A, Lewis MJ, Rivellese F, Pitzalis C, Hughes LB, Horowitz D, DiCarlo E, Gravallese EM, Boyce BF; Accelerating Medicines Partnership: RA/SLE Network; Moreland LW, Goodman SM, Perlman H, Holers VM, Liao KP, Filer A, Bykerk VP, Wei K, Rao DA, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S. Zhang F, et al. Among authors: rumker l. Nature. 2023 Nov;623(7987):616-624. doi: 10.1038/s41586-023-06708-y. Epub 2023 Nov 8. Nature. 2023. PMID: 37938773 Free PMC article.
Efficient and precise single-cell reference atlas mapping with Symphony.
Kang JB, Nathan A, Weinand K, Zhang F, Millard N, Rumker L, Moody DB, Korsunsky I, Raychaudhuri S. Kang JB, et al. Among authors: rumker l. Nat Commun. 2021 Oct 7;12(1):5890. doi: 10.1038/s41467-021-25957-x. Nat Commun. 2021. PMID: 34620862 Free PMC article.
Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease.
Sakaue S, Gurajala S, Curtis M, Luo Y, Choi W, Ishigaki K, Kang JB, Rumker L, Deutsch AJ, Schönherr S, Forer L, LeFaive J, Fuchsberger C, Han B, Lenz TL, de Bakker PIW, Okada Y, Smith AV, Raychaudhuri S. Sakaue S, et al. Among authors: rumker l. Nat Protoc. 2023 Sep;18(9):2625-2641. doi: 10.1038/s41596-023-00853-4. Epub 2023 Jul 26. Nat Protoc. 2023. PMID: 37495751 Free PMC article. Review.
Associations Between Rheumatoid Arthritis Clinical Factors and Synovial Cell Types and States.
Weisenfeld D, Zhang F, Donlin L, Jonsson AH, Apruzzese W, Campbell D; Accelerating Medicines Partnership Program: RA/SLE Network; Rao DA, Wei K, Holers VM, Gravallese E, Moreland L, Goodman S, Brenner M, Raychaudhuri S, Filer A, Anolik J, Bykerk V, Liao KP. Weisenfeld D, et al. Arthritis Rheumatol. 2024 Mar;76(3):356-362. doi: 10.1002/art.42726. Epub 2024 Jan 19. Arthritis Rheumatol. 2024. PMID: 37791989
Designing sensitive viral diagnostics with machine learning.
Metsky HC, Welch NL, Pillai PP, Haradhvala NJ, Rumker L, Mantena S, Zhang YB, Yang DK, Ackerman CM, Weller J, Blainey PC, Myhrvold C, Mitzenmacher M, Sabeti PC. Metsky HC, et al. Among authors: rumker l. Nat Biotechnol. 2022 Jul;40(7):1123-1131. doi: 10.1038/s41587-022-01213-5. Epub 2022 Mar 3. Nat Biotechnol. 2022. PMID: 35241837 Free PMC article.
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis.
Faust HJ, Cheng TY, Korsunsky I, Watts GFM, Gal-Oz ST, Trim WV, Kongthong S, Jonsson AH, Simmons DP, Zhang F, Padera R, Chubinskaya S; Accelerating Medicines Partnership: RA/SLE Network; Wei K, Raychaudhuri S, Lynch L, Moody DB, Brenner MB. Faust HJ, et al. Nat Commun. 2024 Nov 14;15(1):9859. doi: 10.1038/s41467-024-52586-x. Nat Commun. 2024. PMID: 39543086 Free PMC article.
20 results