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The RORɣ/SREBP2 pathway is a master regulator of cholesterol metabolism and serves as potential therapeutic target in t(4;11) leukemia.
Erkner E, Hentrich T, Schairer R, Fitzel R, Secker-Grob KA, Jeong J, Keppeler H, Korkmaz F, Schulze-Hentrich JM, Lengerke C, Schneidawind D, Schneidawind C. Erkner E, et al. Among authors: keppeler h. Oncogene. 2024 Jan;43(4):281-293. doi: 10.1038/s41388-023-02903-3. Epub 2023 Nov 29. Oncogene. 2024. PMID: 38030791 Free PMC article.
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.
Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, Campbell DG, Fehrenbacher B, Schaller M, Wesselborg S, Stork B. Alers S, et al. Among authors: keppeler h. Autophagy. 2011 Dec;7(12):1423-33. doi: 10.4161/auto.7.12.18027. Autophagy. 2011. PMID: 22024743 Free PMC article.
Moonlighting osteoclasts as undertakers of apoptotic cells.
Harre U, Keppeler H, Ipseiz N, Derer A, Poller K, Aigner M, Schett G, Herrmann M, Lauber K. Harre U, et al. Among authors: keppeler h. Autoimmunity. 2012 Dec;45(8):612-9. doi: 10.3109/08916934.2012.719950. Epub 2012 Oct 11. Autoimmunity. 2012. PMID: 22978425
Invariant NKT Cells From Donor Lymphocyte Infusions (DLI-iNKTs) Promote ex vivo Lysis of Leukemic Blasts in a CD1d-Dependent Manner.
Jahnke S, Schmid H, Secker KA, Einhaus J, Duerr-Stoerzer S, Keppeler H, Schober-Melms I, Baur R, Schumm M, Handgretinger R, Bethge W, Kanz L, Schneidawind C, Schneidawind D. Jahnke S, et al. Among authors: keppeler h. Front Immunol. 2019 Jul 9;10:1542. doi: 10.3389/fimmu.2019.01542. eCollection 2019. Front Immunol. 2019. PMID: 31354710 Free PMC article.
Inhibition of effector B cells by ibrutinib in systemic sclerosis.
Einhaus J, Pecher AC, Asteriti E, Schmid H, Secker KA, Duerr-Stoerzer S, Keppeler H, Klein R, Schneidawind C, Henes J, Schneidawind D. Einhaus J, et al. Among authors: keppeler h. Arthritis Res Ther. 2020 Mar 30;22(1):66. doi: 10.1186/s13075-020-02153-8. Arthritis Res Ther. 2020. PMID: 32228672 Free PMC article.
46 results