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SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late-onset Alzheimer's disease.
Jesudason CD, Mason ER, Chu S, Oblak AL, Javens-Wolfe J, Moussaif M, Durst G, Hipskind P, Beck DE, Dong J, Amarasinghe O, Zhang ZY, Hamdani AK, Singhal K, Mesecar AD, Souza S, Jacobson M, Salvo JD, Soni DM, Kandasamy M, Masters AR, Quinney SK, Doolen S, Huhe H, Rizzo SJS, Lamb BT, Palkowitz AD, Richardson TI. Jesudason CD, et al. Among authors: soni dm. Alzheimers Dement (N Y). 2023 Nov 17;9(4):e12429. doi: 10.1002/trc2.12429. eCollection 2023 Oct-Dec. Alzheimers Dement (N Y). 2023. PMID: 38023622 Free PMC article.
Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology.
Potjewyd FM, Annor-Gyamfi JK, Aubé J, Chu S, Conlon IL, Frankowski KJ, Guduru SKR, Hardy BP, Hopkins MD, Kinoshita C, Kireev DB, Mason ER, Moerk CT, Nwogbo F, Pearce KH Jr, Richardson TI, Rogers DA, Soni DM, Stashko M, Wang X, Wells C, Willson TM, Frye SV, Young JE, Axtman AD. Potjewyd FM, et al. Among authors: soni dm. Alzheimers Dement (N Y). 2022 Apr 12;8(1):e12253. doi: 10.1002/trc2.12253. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35434254 Free PMC article.
AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery.
Potjewyd FM, Annor-Gyamfi JK, Aubé J, Chu S, Conlon IL, Frankowski KJ, Guduru SKR, Hardy BP, Hopkins MD, Kinoshita C, Kireev DB, Mason ER, Moerk CT, Nwogbo F, Pearce KH, Richardson TI, Rogers DA, Soni DM, Stashko M, Wang X, Wells C, Willson TM, Frye SV, Young JE, Axtman AD. Potjewyd FM, et al. Among authors: soni dm. Alzheimers Dement (N Y). 2022 Apr 20;8(1):e12246. doi: 10.1002/trc2.12246. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35475262 Free PMC article.
Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.
Oblak AL, Kotredes KP, Pandey RS, Reagan AM, Ingraham C, Perkins B, Lloyd C, Baker D, Lin PB, Soni DM, Tsai AP, Persohn SA, Bedwell AA, Eldridge K, Speedy R, Meyer JA, Peters JS, Figueiredo LL, Sasner M, Territo PR, Sukoff Rizzo SJ, Carter GW, Lamb BT, Howell GR. Oblak AL, et al. Among authors: soni dm. Front Aging Neurosci. 2022 Jun 24;14:886575. doi: 10.3389/fnagi.2022.886575. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35813947 Free PMC article.
TREM2-Deficient Microglia Attenuate Tau Spreading In Vivo.
Lee-Gosselin A, Jury-Garfe N, You Y, Dabin L, Soni D, Dutta S, Rochet JC, Kim J, Oblak AL, Lasagna-Reeves CA. Lee-Gosselin A, et al. Cells. 2023 Jun 10;12(12):1597. doi: 10.3390/cells12121597. Cells. 2023. PMID: 37371067 Free PMC article.
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Sasner M, Preuss C, Pandey RS, Uyar A, Garceau D, Kotredes KP, Williams H, Oblak AL, Lin PB, Perkins B, Soni D, Ingraham C, Lee-Gosselin A, Lamb BT, Howell GR, Carter GW. Sasner M, et al. bioRxiv [Preprint]. 2023 Dec 24:2023.12.21.572849. doi: 10.1101/2023.12.21.572849. bioRxiv. 2023. Update in: Alzheimers Dement. 2024 Jul;20(7):4970-4984. doi: 10.1002/alz.13840 PMID: 38187758 Free PMC article. Updated. Preprint.
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Sasner M, Preuss C, Pandey RS, Uyar A, Garceau D, Kotredes KP, Williams H, Oblak AL, Lin PB, Perkins B, Soni D, Ingraham C, Lee-Gosselin A, Lamb BT, Howell GR, Carter GW. Sasner M, et al. Alzheimers Dement. 2024 Jul;20(7):4970-4984. doi: 10.1002/alz.13840. Epub 2024 Apr 30. Alzheimers Dement. 2024. PMID: 38687251 Free PMC article.
SHIP1 modulation and proteome characterization of microglia.
Ahat E, Shi Z, Chu S, Bui HH, Mason ER, Soni DM, Roth KD, Chalmers MJ, Oblak AL, Zhang J, Gutierrez JA, Richardson T. Ahat E, et al. Among authors: soni dm. J Proteomics. 2024 Jun 30;302:105198. doi: 10.1016/j.jprot.2024.105198. Epub 2024 May 20. J Proteomics. 2024. PMID: 38777089
13 results