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Page 1
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster.
Nolan TM, Deliyannis G, Griffith M, Braat S, Allen LF, Audsley J, Chung AW, Ciula M, Gherardin NA, Giles ML, Gordon TP, Grimley SL, Horng L, Jackson DC, Juno JA, Kedzierska K, Kent SJ, Lewin SR, Littlejohn M, McQuilten HA, Mordant FL, Nguyen THO, Soo VP, Price B, Purcell DFJ, Ramanathan P, Redmond SJ, Rockman S, Ruan Z, Sasadeusz J, Simpson JA, Subbarao K, Fabb SA, Payne TJ, Takanashi A, Tan CW, Torresi J, Wang JJ, Wang LF, Al-Wassiti H, Wong CY, Zaloumis S, Pouton CW, Godfrey DI. Nolan TM, et al. Among authors: grimley sl. EBioMedicine. 2023 Dec;98:104878. doi: 10.1016/j.ebiom.2023.104878. Epub 2023 Nov 27. EBioMedicine. 2023. PMID: 38016322 Free PMC article. Clinical Trial.
Infrared Based Saliva Screening Test for COVID-19.
Wood BR, Kochan K, Bedolla DE, Salazar-Quiroz N, Grimley SL, Perez-Guaita D, Baker MJ, Vongsvivut J, Tobin MJ, Bambery KR, Christensen D, Pasricha S, Eden AK, Mclean A, Roy S, Roberts JA, Druce J, Williamson DA, McAuley J, Catton M, Purcell DFJ, Godfrey DI, Heraud P. Wood BR, et al. Among authors: grimley sl. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17102-17107. doi: 10.1002/anie.202104453. Epub 2021 Jun 29. Angew Chem Int Ed Engl. 2021. PMID: 34043272 Free PMC article.
Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay.
Lopez E, Haycroft ER, Adair A, Mordant FL, O'Neill MT, Pymm P, Redmond SJ, Lee WS, Gherardin NA, Wheatley AK, Juno JA, Selva KJ, Davis SK, Grimley SL, Harty L, Purcell DF, Subbarao K, Godfrey DI, Kent SJ, Tham WH, Chung AW. Lopez E, et al. Among authors: grimley sl. JCI Insight. 2021 Aug 23;6(16):e150012. doi: 10.1172/jci.insight.150012. JCI Insight. 2021. PMID: 34251356 Free PMC article.
A point-of-care lateral flow assay for neutralising antibodies against SARS-CoV-2.
Fulford TS, Van H, Gherardin NA, Zheng S, Ciula M, Drummer HE, Redmond S, Tan HX, Boo I, Center RJ, Li F, Grimley SL, Wines BD, Nguyen THO, Mordant FL, Ellenberg P, Rowntree LC, Kedzierski L, Cheng AC, Doolan DL, Matthews G, Bond K, Hogarth PM, McQuilten Z, Subbarao K, Kedzierska K, Juno JA, Wheatley AK, Kent SJ, Williamson DA, Purcell DFJ, Anderson DA, Godfrey DI. Fulford TS, et al. Among authors: grimley sl. EBioMedicine. 2021 Dec;74:103729. doi: 10.1016/j.ebiom.2021.103729. Epub 2021 Dec 3. EBioMedicine. 2021. PMID: 34871960 Free PMC article.
Air-Liquid-Interface Differentiated Human Nose Epithelium: A Robust Primary Tissue Culture Model of SARS-CoV-2 Infection.
Tran BM, Grimley SL, McAuley JL, Hachani A, Earnest L, Wong SL, Caly L, Druce J, Purcell DFJ, Jackson DC, Catton M, Nowell CJ, Leonie L, Deliyannis G, Waters SA, Torresi J, Vincan E. Tran BM, et al. Among authors: grimley sl. Int J Mol Sci. 2022 Jan 13;23(2):835. doi: 10.3390/ijms23020835. Int J Mol Sci. 2022. PMID: 35055020 Free PMC article.
Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2.
Pymm P, Redmond SJ, Dolezal O, Mordant F, Lopez E, Cooney JP, Davidson KC, Haycroft ER, Tan CW, Seneviratna R, Grimley SL, Purcell DFJ, Kent SJ, Wheatley AK, Wang LF, Leis A, Glukhova A, Pellegrini M, Chung AW, Subbarao K, Uldrich AP, Tham WH, Godfrey DI, Gherardin NA. Pymm P, et al. Among authors: grimley sl. iScience. 2022 Nov 18;25(11):105259. doi: 10.1016/j.isci.2022.105259. Epub 2022 Oct 4. iScience. 2022. PMID: 36213007 Free PMC article.
Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine.
Deliyannis G, Gherardin NA, Wong CY, Grimley SL, Cooney JP, Redmond SJ, Ellenberg P, Davidson KC, Mordant FL, Smith T, Gillard M, Lopez E, McAuley J, Tan CW, Wang JJ, Zeng W, Littlejohn M, Zhou R, Fuk-Woo Chan J, Chen ZW, Hartwig AE, Bowen R, Mackenzie JM, Vincan E, Torresi J, Kedzierska K, Pouton CW, Gordon TP, Wang LF, Kent SJ, Wheatley AK, Lewin SR, Subbarao K, Chung AW, Pellegrini M, Munro T, Nolan T, Rockman S, Jackson DC, Purcell DFJ, Godfrey DI. Deliyannis G, et al. Among authors: grimley sl. EBioMedicine. 2023 Jun;92:104574. doi: 10.1016/j.ebiom.2023.104574. Epub 2023 May 4. EBioMedicine. 2023. PMID: 37148585 Free PMC article.
SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates.
Bader SM, Cooney JP, Sheerin D, Taiaroa G, Harty L, Davidson KC, Mackiewicz L, Dayton M, Wilcox S, Whitehead L, Rogers KL, Georgy SR, Coussens AK, Grimley SL, Corbin V, Pitt M, Coin L, Pickering R, Thomas M, Allison CC, McAuley J, Purcell DFJ, Doerflinger M, Pellegrini M. Bader SM, et al. Among authors: grimley sl. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2301689120. doi: 10.1073/pnas.2301689120. Epub 2023 Jul 31. Proc Natl Acad Sci U S A. 2023. PMID: 37523564 Free PMC article.
Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia.
Chang JJ, Grimley SL, Tran BM, Deliyannis G, Tumpach C, Nguyen ANT, Steinig E, Zhang J, Schröder J, Caly L, McAuley J, Wong SL, Waters SA, Stinear TP, Pitt ME, Purcell D, Vincan E, Coin LJM. Chang JJ, et al. Among authors: grimley sl. iScience. 2024 May 17;27(6):110009. doi: 10.1016/j.isci.2024.110009. eCollection 2024 Jun 21. iScience. 2024. PMID: 38868206 Free PMC article.
16 results