Lin PB - Search Results

1

Therapeutic targeting of immunometabolism in Alzheimer's disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression.

Codocedo JF, Mera-Reina C, Lin PB, Puntambekar SS, Casali BT, Jury N, Martinez P, Lasagna-Reeves CA, Landreth GE. Codocedo JF, et al. Among authors: lin pb. bioRxiv [Preprint]. 2023 Nov 15:2023.11.11.566270. doi: 10.1101/2023.11.11.566270. bioRxiv. 2023. Update in: Cell Rep. 2024 Jul 23;43(7):114488. doi: 10.1016/j.celrep.2024.114488. PMID: 38014106 Free PMC article. Updated. Preprint.

2

INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia.

Tsai AP, Lin PB, Dong C, Moutinho M, Casali BT, Liu Y, Lamb BT, Landreth GE, Oblak AL, Nho K. Tsai AP, et al. Among authors: lin pb. Neurobiol Dis. 2021 Jun;153:105303. doi: 10.1016/j.nbd.2021.105303. Epub 2021 Feb 22. Neurobiol Dis. 2021. PMID: 33631273 Free PMC article.

3

PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer's disease.

Tsai AP, Dong C, Lin PB, Messenger EJ, Casali BT, Moutinho M, Liu Y, Oblak AL, Lamb BT, Landreth GE, Bissel SJ, Nho K. Tsai AP, et al. Among authors: lin pb. Genome Med. 2022 Feb 18;14(1):17. doi: 10.1186/s13073-022-01022-0. Genome Med. 2022. PMID: 35180881 Free PMC article.

4

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.

Moutinho M, Puntambekar SS, Tsai AP, Coronel I, Lin PB, Casali BT, Martinez P, Oblak AL, Lasagna-Reeves CA, Lamb BT, Landreth GE. Moutinho M, et al. Among authors: lin pb. Sci Transl Med. 2022 Mar 23;14(637):eabl7634. doi: 10.1126/scitranslmed.abl7634. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320002 Free PMC article.

5

CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer's disease.

Puntambekar SS, Moutinho M, Lin PB, Jadhav V, Tumbleson-Brink D, Balaji A, Benito MA, Xu G, Oblak A, Lasagna-Reeves CA, Landreth GE, Lamb BT. Puntambekar SS, et al. Among authors: lin pb. Mol Neurodegener. 2022 Jun 28;17(1):47. doi: 10.1186/s13024-022-00545-9. Mol Neurodegener. 2022. PMID: 35764973 Free PMC article.

6

Corrigendum: Age-dependent microstructure alterations in 5xFAD mice by high-resolution diffusion tensor imaging.

Maharjan S, Tsai AP, Lin PB, Ingraham C, Jewett MR, Landreth GE, Oblak AL, Wang N. Maharjan S, et al. Among authors: lin pb. Front Neurosci. 2022 Oct 13;16:1025457. doi: 10.3389/fnins.2022.1025457. eCollection 2022. Front Neurosci. 2022. PMID: 36312018 Free PMC article.

7

Integrating multimodality magnetic resonance imaging to the Allen Mouse Brain Common Coordinate Framework.

Wang N, Maharjan S, Tsai AP, Lin PB, Qi Y, Wallace A, Jewett M, Liu F, Landreth GE, Oblak AL. Wang N, et al. Among authors: lin pb. NMR Biomed. 2023 May;36(5):e4887. doi: 10.1002/nbm.4887. Epub 2022 Dec 22. NMR Biomed. 2023. PMID: 36454009 Free PMC article.

8

INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease.

Lin PB, Tsai AP, Soni D, Lee-Gosselin A, Moutinho M, Puntambekar SS, Landreth GE, Lamb BT, Oblak AL. Lin PB, et al. Alzheimers Dement. 2023 Jun;19(6):2528-2537. doi: 10.1002/alz.12849. Epub 2022 Dec 16. Alzheimers Dement. 2023. PMID: 36524682

9

Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease.

Tsai AP, Dong C, Lin PB, Oblak AL, Viana Di Prisco G, Wang N, Hajicek N, Carr AJ, Lendy EK, Hahn O, Atkins M, Foltz AG, Patel J, Xu G, Moutinho M, Sondek J, Zhang Q, Mesecar AD, Liu Y, Atwood BK, Wyss-Coray T, Nho K, Bissel SJ, Lamb BT, Landreth GE. Tsai AP, et al. Among authors: lin pb. Immunity. 2023 Sep 12;56(9):2121-2136.e6. doi: 10.1016/j.immuni.2023.08.008. Epub 2023 Sep 1. Immunity. 2023. PMID: 37659412 Free PMC article.

10

Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer's Disease.

Reilly AM, Tsai AP, Lin PB, Ericsson AC, Oblak AL, Ren H. Reilly AM, et al. Among authors: lin pb. Nutrients. 2020 Sep 29;12(10):2977. doi: 10.3390/nu12102977. Nutrients. 2020. PMID: 33003412 Free PMC article.

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