Chen S - Search Results

1

Integrated multi-omics single cell atlas of the human retina.

Li J, Wang J, Ibarra IL, Cheng X, Luecken MD, Lu J, Monavarfeshani A, Yan W, Zheng Y, Zuo Z, Colborn SLZ, Cortez BS, Owen LA, Tran NM, Shekhar K, Sanes JR, Stout JT, Chen S, Li Y, DeAngelis MM, Theis FJ, Chen R. Li J, et al. Among authors: chen r, chen s. Res Sq [Preprint]. 2023 Nov 17:rs.3.rs-3471275. doi: 10.21203/rs.3.rs-3471275/v1. Res Sq. 2023. PMID: 38014002 Free PMC article. Preprint.

2

Transcriptional regulation of neural retina leucine zipper (Nrl), a photoreceptor cell fate determinant.

Montana CL, Lawrence KA, Williams NL, Tran NM, Peng GH, Chen S, Corbo JC. Montana CL, et al. Among authors: chen s. J Biol Chem. 2011 Oct 21;286(42):36921-31. doi: 10.1074/jbc.M111.279026. Epub 2011 Aug 24. J Biol Chem. 2011. PMID: 21865162 Free PMC article.

3

Mechanistically distinct mouse models for CRX-associated retinopathy.

Tran NM, Zhang A, Zhang X, Huecker JB, Hennig AK, Chen S. Tran NM, et al. Among authors: chen s. PLoS Genet. 2014 Feb 6;10(2):e1004111. doi: 10.1371/journal.pgen.1004111. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24516401 Free PMC article.

4

Mechanisms of blindness: animal models provide insight into distinct CRX-associated retinopathies.

Tran NM, Chen S. Tran NM, et al. Among authors: chen s. Dev Dyn. 2014 Oct;243(10):1153-66. doi: 10.1002/dvdy.24151. Epub 2014 Jun 27. Dev Dyn. 2014. PMID: 24888636 Free PMC article. Review.

5

Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies.

Ruzycki PA, Tran NM, Kefalov VJ, Kolesnikov AV, Chen S. Ruzycki PA, et al. Among authors: chen s. Genome Biol. 2015 Sep 1;16(1):171. doi: 10.1186/s13059-015-0732-z. Genome Biol. 2015. PMID: 26324254 Free PMC article.

6

CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis.

Occelli LM, Tran NM, Narfström K, Chen S, Petersen-Jones SM. Occelli LM, et al. Among authors: chen s. Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3780-92. doi: 10.1167/iovs.16-19444. Invest Ophthalmol Vis Sci. 2016. PMID: 27427859 Free PMC article.

7

Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms.

Zheng Y, Sun C, Zhang X, Ruzycki PA, Chen S. Zheng Y, et al. Among authors: chen s. bioRxiv [Preprint]. 2023 Jun 15:2023.02.01.526652. doi: 10.1101/2023.02.01.526652. bioRxiv. 2023. Update in: Elife. 2023 Nov 14;12:RP87147. doi: 10.7554/eLife.87147. PMID: 36778408 Free PMC article. Updated. Preprint.

8

Pathogenic variants in Crx have distinct cis-regulatory effects on enhancers and silencers in photoreceptors.

Shepherdson JL, Friedman RZ, Zheng Y, Sun C, Oh IY, Granas DM, Cohen BA, Chen S, White MA. Shepherdson JL, et al. Among authors: chen s. bioRxiv [Preprint]. 2023 Dec 2:2023.05.27.542576. doi: 10.1101/2023.05.27.542576. bioRxiv. 2023. Update in: Genome Res. 2024 Mar 20;34(2):243-255. doi: 10.1101/gr.278133.123. PMID: 37292699 Free PMC article. Updated. Preprint.

9

Cat LCA-CRX Model, Homozygous for an Antimorphic Mutation Has a Unique Phenotype.

Occelli LM, Tran NM, Chen S, Petersen-Jones SM. Occelli LM, et al. Among authors: chen s. Transl Vis Sci Technol. 2023 Jun 1;12(6):15. doi: 10.1167/tvst.12.6.15. Transl Vis Sci Technol. 2023. PMID: 37351895 Free PMC article.

10

Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms.

Zheng Y, Sun C, Zhang X, Ruzycki PA, Chen S. Zheng Y, et al. Among authors: chen s. Elife. 2023 Nov 14;12:RP87147. doi: 10.7554/eLife.87147. Elife. 2023. PMID: 37963072 Free PMC article.

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