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Page 1
The transcriptional and phenotypic characteristics that define alveolar macrophage subsets in acute hypoxemic respiratory failure.
Morrell ED, Holton SE, Lawrance M, Orlov M, Franklin Z, Mitchem MA, DeBerg H, Gersuk VH, Garay A, Barnes E, Liu T, Peltan ID, Rogers A, Ziegler S, Wurfel MM, Mikacenic C. Morrell ED, et al. Among authors: mitchem ma. Nat Commun. 2023 Nov 17;14(1):7443. doi: 10.1038/s41467-023-43223-0. Nat Commun. 2023. PMID: 37978185 Free PMC article.
Chemokines, soluble PD-L1, and immune cell hyporesponsiveness are distinct features of SARS-CoV-2 critical illness.
Morrell ED, Bhatraju PK, Sathe NA, Lawson J, Mabrey L, Holton SE, Presnell SR, Wiedeman A, Acosta-Vega C, Mitchem MA, Liu T, Chai XY, Sahi S, Brager C, Orlov M, Sakr SS, Sader A, Lum DM, Koetje N, Garay A, Barnes E, Cromer G, Bray MK, Pipavath S, Fink SL, Evans L, Long SA, West TE, Wurfel MM, Mikacenic C. Morrell ED, et al. Among authors: mitchem ma. Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1;323(1):L14-L26. doi: 10.1152/ajplung.00049.2022. Epub 2022 May 24. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35608267 Free PMC article.
Mediators of monocyte chemotaxis and matrix remodeling are associated with the development of fibrosis in patients with COVID-19.
Holton SE, Mitchem M, Pipavath S, Morrell ED, Bhatraju PK, Hamerman JA, Speake C, Malhotra U, Wurfel MM, Ziegler S, Mikacenic C. Holton SE, et al. medRxiv [Preprint]. 2023 May 1:2023.04.28.23289261. doi: 10.1101/2023.04.28.23289261. medRxiv. 2023. Update in: PLoS One. 2024 Aug 6;19(8):e0285638. doi: 10.1371/journal.pone.0285638. PMID: 37205332 Free PMC article. Updated. Preprint.
PD-L1 and PD-1 Are Associated with Clinical Outcomes and Alveolar Immune Cell Activation in Acute Respiratory Distress Syndrome.
Morrell ED, Holton SE, Wiedeman A, Kosamo S, Mitchem MA, Dmyterko V, Franklin Z, Garay A, Stanaway IB, Liu T, Sathe NA, Mabrey FL, Stapleton RD, Malhotra U, Speake C, Hamerman JA, Pipavath S, Evans L, Bhatraju PK, Long SA, Wurfel MM, Mikacenic C. Morrell ED, et al. Among authors: mitchem ma. Am J Respir Cell Mol Biol. 2024 Nov;71(5):534-545. doi: 10.1165/rcmb.2024-0201OC. Am J Respir Cell Mol Biol. 2024. PMID: 38950166