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Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors.
Mavrommatis L, Jeong HW, Kindler U, Gomez-Giro G, Kienitz MC, Stehling M, Psathaki OE, Zeuschner D, Bixel MG, Han D, Morosan-Puopolo G, Gerovska D, Yang JH, Kim JB, Arauzo-Bravo MJ, Schwamborn JC, Hahn SA, Adams RH, Schöler HR, Vorgerd M, Brand-Saberi B, Zaehres H. Mavrommatis L, et al. Among authors: han d. Elife. 2023 Nov 14;12:RP87081. doi: 10.7554/eLife.87081. Elife. 2023. PMID: 37963071 Free PMC article.
A balanced Oct4 interactome is crucial for maintaining pluripotency.
Han D, Wu G, Chen R, Drexler HCA, MacCarthy CM, Kim KP, Adachi K, Gerovska D, Mavrommatis L, Bedzhov I, Araúzo-Bravo MJ, Schöler HR. Han D, et al. Sci Adv. 2022 Feb 18;8(7):eabe4375. doi: 10.1126/sciadv.abe4375. Epub 2022 Feb 16. Sci Adv. 2022. PMID: 35171666 Free PMC article.
A unique Oct4 interface is crucial for reprogramming to pluripotency.
Esch D, Vahokoski J, Groves MR, Pogenberg V, Cojocaru V, Vom Bruch H, Han D, Drexler HC, Araúzo-Bravo MJ, Ng CK, Jauch R, Wilmanns M, Schöler HR. Esch D, et al. Among authors: han d. Nat Cell Biol. 2013 Mar;15(3):295-301. doi: 10.1038/ncb2680. Epub 2013 Feb 3. Nat Cell Biol. 2013. PMID: 23376973
Establishment of totipotency does not depend on Oct4A.
Wu G, Han D, Gong Y, Sebastiano V, Gentile L, Singhal N, Adachi K, Fischedick G, Ortmeier C, Sinn M, Radstaak M, Tomilin A, Schöler HR. Wu G, et al. Among authors: han d. Nat Cell Biol. 2013 Sep;15(9):1089-97. doi: 10.1038/ncb2816. Epub 2013 Aug 11. Nat Cell Biol. 2013. PMID: 23934214 Free PMC article.
10,857 results
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