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Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation.
Knight H, Abis G, Kaur M, Green HLH, Krasemann S, Hartmann K, Lynham S, Clark J, Zhao L, Ruppert C, Weiss A, Schermuly RT, Eaton P, Rudyk O. Knight H, et al. Among authors: ruppert c. Circ Res. 2023 Dec 8;133(12):966-988. doi: 10.1161/CIRCRESAHA.122.321836. Epub 2023 Nov 13. Circ Res. 2023. PMID: 37955182 Free PMC article.
Is the fibroblast growth factor signaling pathway a victim of receptor tyrosine kinase inhibition in pulmonary parenchymal and vascular remodeling?
El Agha E, Schwind F, Ruppert C, Günther A, Bellusci S, Schermuly RT, Kosanovic D. El Agha E, et al. Among authors: ruppert c. Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L248-L252. doi: 10.1152/ajplung.00140.2018. Epub 2018 May 3. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29722558 Free article.
Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension.
Weiss A, Neubauer MC, Yerabolu D, Kojonazarov B, Schlueter BC, Neubert L, Jonigk D, Baal N, Ruppert C, Dorfmuller P, Pullamsetti SS, Weissmann N, Ghofrani HA, Grimminger F, Seeger W, Schermuly RT. Weiss A, et al. Among authors: ruppert c. Nat Commun. 2019 May 17;10(1):2204. doi: 10.1038/s41467-019-10135-x. Nat Commun. 2019. PMID: 31101827 Free PMC article.
Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension.
Rudyk O, Rowan A, Prysyazhna O, Krasemann S, Hartmann K, Zhang M, Shah AM, Ruppert C, Weiss A, Schermuly RT, Ida T, Akaike T, Zhao L, Eaton P. Rudyk O, et al. Among authors: ruppert c. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13016-13025. doi: 10.1073/pnas.1904064116. Epub 2019 Jun 11. Proc Natl Acad Sci U S A. 2019. PMID: 31186362 Free PMC article.
Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension.
Yerabolu D, Weiss A, Kojonazarov B, Boehm M, Schlueter BC, Ruppert C, Günther A, Jonigk D, Grimminger F, Ghofrani HA, Seeger W, Weissmann N, Schermuly RT. Yerabolu D, et al. Among authors: ruppert c. Am J Respir Cell Mol Biol. 2021 Jan;64(1):100-114. doi: 10.1165/rcmb.2019-0431OC. Am J Respir Cell Mol Biol. 2021. PMID: 33052714
Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension.
Rai N, Sydykov A, Kojonazarov B, Wilhelm J, Manaud G, Veeroju S, Ruppert C, Perros F, Ghofrani HA, Weissmann N, Seeger W, Schermuly RT, Novoyatleva T. Rai N, et al. Among authors: ruppert c. Eur Respir J. 2022 Aug 25;60(2):2101698. doi: 10.1183/13993003.01698-2021. Print 2022 Aug. Eur Respir J. 2022. PMID: 35058248 Free PMC article.
Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival.
Kudryashova TV, Dabral S, Nayakanti S, Ray A, Goncharov DA, Avolio T, Shen Y, Rode A, Pena A, Jiang L, Lin D, Baust J, Bachman TN, Graumann J, Ruppert C, Guenther A, Schmoranzer M, Grobs Y, Eve Lemay S, Tremblay E, Breuils-Bonnet S, Boucherat O, Mora AL, DeLisser H, Zhao J, Zhao Y, Bonnet S, Seeger W, Pullamsetti SS, Goncharova EA. Kudryashova TV, et al. Among authors: ruppert c. Circ Res. 2022 Mar 4;130(5):760-778. doi: 10.1161/CIRCRESAHA.121.319100. Epub 2022 Feb 7. Circ Res. 2022. PMID: 35124974 Free PMC article.
176 results