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Pro-inflammatory GPR75 and anti-apoptotic phospholipase signaling pathways contribute to the ameliorating effect of soluble epoxide hydrolase inhibition on chronic experimental autoimmune encephalomyelitis in mice.
Horat MF, Senol SP, Bahceli O, Temiz-Resitoglu M, Sahan-Firat S, Sevim S, Tunctan B. Horat MF, et al. Among authors: sahan firat s. Cell Mol Biol (Noisy-le-grand). 2023 Oct 31;69(10):9-16. doi: 10.14715/cmb/2023.69.10.2. Cell Mol Biol (Noisy-le-grand). 2023. PMID: 37953590
Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways in an inflammasome-dependent and -independent manner.
Biliktu M, Senol SP, Temiz-Resitoglu M, Guden DS, Horat MF, Sahan-Firat S, Sevim S, Tunctan B. Biliktu M, et al. Among authors: sahan firat s. Inflammopharmacology. 2020 Dec;28(6):1509-1524. doi: 10.1007/s10787-020-00691-w. Epub 2020 Mar 3. Inflammopharmacology. 2020. PMID: 32128702
Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome-related pro-inflammatory and anti-inflammatory signaling pathways in the lipopolysaccharide-induced pain mouse model.
Cagli A, Senol SP, Temiz-Resitoglu M, Guden DS, Sari AN, Sahan-Firat S, Tunctan B. Cagli A, et al. Among authors: sahan firat s. Drug Dev Res. 2021 Sep;82(6):815-825. doi: 10.1002/ddr.21786. Epub 2021 Feb 8. Drug Dev Res. 2021. PMID: 33559150
mTOR inhibition as a possible pharmacological target in the management of systemic inflammatory response and associated neuroinflammation by lipopolysaccharide challenge in rats.
Guden DS, Temiz-Resitoglu M, Senol SP, Kibar D, Yilmaz SN, Tunctan B, Malik KU, Sahan-Firat S. Guden DS, et al. Among authors: sahan firat s. Can J Physiol Pharmacol. 2021 Sep;99(9):921-934. doi: 10.1139/cjpp-2020-0487. Epub 2021 Feb 27. Can J Physiol Pharmacol. 2021. PMID: 33641344
Activation of GPR75 Signaling Pathway Contributes to the Effect of a 20-HETE Mimetic, 5,14-HEDGE, to Prevent Hypotensive and Tachycardic Responses to Lipopolysaccharide in a Rat Model of Septic Shock.
Tunctan B, Senol SP, Temiz-Resitoglu M, Yilmaz DE, Guden DS, Bahceli O, Horat MF, Sahan-Firat S, Sari AN, Falck JR, Anugu RR, Malik KU. Tunctan B, et al. Among authors: sahan firat s. J Cardiovasc Pharmacol. 2022 Aug 1;80(2):276-293. doi: 10.1097/FJC.0000000000001265. J Cardiovasc Pharmacol. 2022. PMID: 35323151
38 results