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Augmented Concentration of Isopentyl-Deoxynyboquinone in Tumors Selectively Kills NAD(P)H Quinone Oxidoreductase 1-Positive Cancer Cells through Programmed Necrotic and Apoptotic Mechanisms.
Wang J, Su X, Jiang L, Boudreau MW, Chatkewitz LE, Kilgore JA, Zahid KR, Williams NS, Chen Y, Liu S, Hergenrother PJ, Huang X. Wang J, et al. Among authors: chatkewitz le. Cancers (Basel). 2023 Dec 14;15(24):5844. doi: 10.3390/cancers15245844. Cancers (Basel). 2023. PMID: 38136388 Free PMC article.
Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill NQO1-Positive Pancreatic Cancer Cells.
Jiang L, Liu Y, Tumbath S, Boudreau MW, Chatkewitz LE, Wang J, Su X, Zahid KR, Li K, Chen Y, Yang K, Hergenrother PJ, Huang X. Jiang L, et al. Among authors: chatkewitz le. Antioxid Redox Signal. 2024 Jul;41(1-3):74-92. doi: 10.1089/ars.2022.0224. Epub 2024 Jan 8. Antioxid Redox Signal. 2024. PMID: 37950707