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Page 1
The power and potential of mitochondria transfer.
Borcherding N, Brestoff JR. Borcherding N, et al. Among authors: brestoff jr. Nature. 2023 Nov;623(7986):283-291. doi: 10.1038/s41586-023-06537-z. Epub 2023 Nov 8. Nature. 2023. PMID: 37938702 Free PMC article. Review.
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D. Rosina M, et al. Among authors: brestoff jr. Cell Metab. 2022 Apr 5;34(4):533-548.e12. doi: 10.1016/j.cmet.2022.02.016. Epub 2022 Mar 18. Cell Metab. 2022. PMID: 35305295 Free PMC article.
Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.
Borcherding N, Jia W, Giwa R, Field RL, Moley JR, Kopecky BJ, Chan MM, Yang BQ, Sabio JM, Walker EC, Osorio O, Bredemeyer AL, Pietka T, Alexander-Brett J, Morley SC, Artyomov MN, Abumrad NA, Schilling J, Lavine K, Crewe C, Brestoff JR. Borcherding N, et al. Among authors: brestoff jr. Cell Metab. 2022 Oct 4;34(10):1499-1513.e8. doi: 10.1016/j.cmet.2022.08.010. Epub 2022 Sep 6. Cell Metab. 2022. PMID: 36070756 Free PMC article.
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.
Brestoff JR, Wilen CB, Moley JR, Li Y, Zou W, Malvin NP, Rowen MN, Saunders BT, Ma H, Mack MR, Hykes BL Jr, Balce DR, Orvedahl A, Williams JW, Rohatgi N, Wang X, McAllaster MR, Handley SA, Kim BS, Doench JG, Zinselmeyer BH, Diamond MS, Virgin HW, Gelman AE, Teitelbaum SL. Brestoff JR, et al. Cell Metab. 2021 Feb 2;33(2):270-282.e8. doi: 10.1016/j.cmet.2020.11.008. Epub 2020 Dec 4. Cell Metab. 2021. PMID: 33278339 Free PMC article.
A guide to studying mitochondria transfer.
Tiash S, Brestoff JR, Crewe C. Tiash S, et al. Among authors: brestoff jr. Nat Cell Biol. 2023 Nov;25(11):1551-1553. doi: 10.1038/s41556-023-01246-1. Nat Cell Biol. 2023. PMID: 37853133 No abstract available.
Hepatic lipids promote liver metastasis.
Li Y, Su X, Rohatgi N, Zhang Y, Brestoff JR, Shoghi KI, Xu Y, Semenkovich CF, Harris CA, Peterson LL, Weilbaecher KN, Teitelbaum SL, Zou W. Li Y, et al. Among authors: brestoff jr. JCI Insight. 2020 Sep 3;5(17):e136215. doi: 10.1172/jci.insight.136215. JCI Insight. 2020. PMID: 32879136 Free PMC article.
53 results