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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, Szymborska A, Rosa A, Nordling S, Schimmel L, Akmeriç EB, Pena A, Nwadozi E, Jamalpour M, Holstein K, Sáinz-Jaspeado M, Bernabeu MO, Welsh M, Gordon E, Franco CA, Vestweber D, Eklund L, Gerhardt H, Claesson-Welsh L. Jin Y, et al. Among authors: pena a. Nat Cardiovasc Res. 2022 Dec 7;1(12):1156-1173. doi: 10.1038/s44161-022-00172-z. Nat Cardiovasc Res. 2022. PMID: 37936984 Free PMC article.
Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy.
Prahst C, Ashrafzadeh P, Mead T, Figueiredo A, Chang K, Richardson D, Venkaraman L, Richards M, Russo AM, Harrington K, Ouarné M, Pena A, Chen DF, Claesson-Welsh L, Cho KS, Franco CA, Bentley K. Prahst C, et al. Among authors: pena a. Elife. 2020 Feb 19;9:e49779. doi: 10.7554/eLife.49779. Elife. 2020. PMID: 32073398 Free PMC article.
Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina.
Barbacena P, Dominguez-Cejudo M, Fonseca CG, Gómez-González M, Faure LM, Zarkada G, Pena A, Pezzarossa A, Ramalho D, Giarratano Y, Ouarné M, Barata D, Fortunato IC, Misikova LH, Mauldin I, Carvalho Y, Trepat X, Roca-Cusachs P, Eichmann A, Bernabeu MO, Franco CA. Barbacena P, et al. Among authors: pena a. Dev Cell. 2022 Oct 10;57(19):2321-2333.e9. doi: 10.1016/j.devcel.2022.09.002. Dev Cell. 2022. PMID: 36220082 Free PMC article.
Endothelial cell invasion is controlled by dactylopodia.
Figueiredo AM, Barbacena P, Russo A, Vaccaro S, Ramalho D, Pena A, Lima AP, Ferreira RR, Fidalgo MA, El-Marjou F, Carvalho Y, Vasconcelos FF, Lennon-Duménil AM, Vignjevic DM, Franco CA. Figueiredo AM, et al. Among authors: pena a. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2023829118. doi: 10.1073/pnas.2023829118. Proc Natl Acad Sci U S A. 2021. PMID: 33903241 Free PMC article.
2,045 results