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Page 1
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.
Miao R, Jiang C, Chang WY, Zhang H, An J, Ho F, Chen P, Zhang H, Junqueira C, Amgalan D, Liang FG, Zhang J, Evavold CL, Hafner-Bratkovič I, Zhang Z, Fontana P, Xia S, Waldeck-Weiermair M, Pan Y, Michel T, Bar-Peled L, Wu H, Kagan JC, Kitsis RN, Zhang P, Liu X, Lieberman J. Miao R, et al. Among authors: kagan jc. Immunity. 2023 Nov 14;56(11):2523-2541.e8. doi: 10.1016/j.immuni.2023.10.004. Epub 2023 Nov 3. Immunity. 2023. PMID: 37924812 Free PMC article.
Gasdermin D pore-forming activity is redox-sensitive.
Devant P, Boršić E, Ngwa EM, Xiao H, Chouchani ET, Thiagarajah JR, Hafner-Bratkovič I, Evavold CL, Kagan JC. Devant P, et al. Among authors: kagan jc. Cell Rep. 2023 Jan 31;42(1):112008. doi: 10.1016/j.celrep.2023.112008. Epub 2023 Jan 19. Cell Rep. 2023. PMID: 36662620 Free PMC article.
Targeting innate immune pathways for cancer immunotherapy.
Cao LL, Kagan JC. Cao LL, et al. Among authors: kagan jc. Immunity. 2023 Oct 10;56(10):2206-2217. doi: 10.1016/j.immuni.2023.07.018. Epub 2023 Sep 12. Immunity. 2023. PMID: 37703879 Free PMC article. Review.
Structural transitions enable interleukin-18 maturation and signaling.
Dong Y, Bonin JP, Devant P, Liang Z, Sever AIM, Mintseris J, Aramini JM, Du G, Gygi SP, Kagan JC, Kay LE, Wu H. Dong Y, et al. Among authors: kagan jc. Immunity. 2024 Jul 9;57(7):1533-1548.e10. doi: 10.1016/j.immuni.2024.04.015. Epub 2024 May 10. Immunity. 2024. PMID: 38733997
Strategies of bacterial detection by inflammasomes.
Jastrab JB, Kagan JC. Jastrab JB, et al. Among authors: kagan jc. Cell Chem Biol. 2024 May 16;31(5):835-850. doi: 10.1016/j.chembiol.2024.03.009. Epub 2024 Apr 17. Cell Chem Biol. 2024. PMID: 38636521 Review.
Inflammasomes as regulators of non-infectious disease.
Okin D, Kagan JC. Okin D, et al. Among authors: kagan jc. Semin Immunol. 2023 Sep;69:101815. doi: 10.1016/j.smim.2023.101815. Epub 2023 Jul 26. Semin Immunol. 2023. PMID: 37506489 Free PMC article. Review.
132 results