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Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress.
Chua V, Lopez-Anton M, Mizue Terai, Ryota Tanaka, Baqai U, Purwin TJ, Haj JI, Waltrich FJ Jr, Trachtenberg I, Luo K, Tudi R, Jeon A, Han A, Chervoneva I, Davies MA, Aguirre-Ghiso JA, Sato T, Aplin AE. Chua V, et al. Among authors: baqai u. Sci Signal. 2024 Jun 11;17(840):eadn8376. doi: 10.1126/scisignal.adn8376. Epub 2024 Jun 11. Sci Signal. 2024. PMID: 38861613
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth.
Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE. Han A, et al. Among authors: baqai u. Cancers (Basel). 2023 Jun 30;15(13):3451. doi: 10.3390/cancers15133451. Cancers (Basel). 2023. PMID: 37444561 Free PMC article.
The future of targeted kinase inhibitors in melanoma.
Caksa S, Baqai U, Aplin AE. Caksa S, et al. Among authors: baqai u. Pharmacol Ther. 2022 Nov;239:108200. doi: 10.1016/j.pharmthera.2022.108200. Epub 2022 May 2. Pharmacol Ther. 2022. PMID: 35513054 Free PMC article. Review.
Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma.
Teh JLF, Purwin TJ, Han A, Chua V, Patel P, Baqai U, Liao C, Bechtel N, Sato T, Davies MA, Aguirre-Ghiso J, Aplin AE. Teh JLF, et al. Among authors: baqai u. Mol Cancer Ther. 2020 Aug;19(8):1719-1726. doi: 10.1158/1535-7163.MCT-19-1016. Epub 2020 May 19. Mol Cancer Ther. 2020. PMID: 32430489 Free PMC article.