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Page 1
Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis.
Salahudeen AA, Seoane JA, Yuki K, Mah AT, Smith AR, Kolahi K, De la O SM, Hart DJ, Ding J, Ma Z, Barkal SA, Shukla ND, Zhang CH, Cantrell MA, Batish A, Usui T, Root DE, Hahn WC, Curtis C, Kuo CJ. Salahudeen AA, et al. Among authors: mah at. Cell Rep. 2023 Nov 28;42(11):113355. doi: 10.1016/j.celrep.2023.113355. Epub 2023 Nov 1. Cell Rep. 2023. PMID: 37922313 Free PMC article.
Deterministic evolution and stringent selection during preneoplasia.
Karlsson K, Przybilla MJ, Kotler E, Khan A, Xu H, Karagyozova K, Sockell A, Wong WH, Liu K, Mah A, Lo YH, Lu B, Houlahan KE, Ma Z, Suarez CJ, Barnes CP, Kuo CJ, Curtis C. Karlsson K, et al. Nature. 2023 Jun;618(7964):383-393. doi: 10.1038/s41586-023-06102-8. Epub 2023 May 31. Nature. 2023. PMID: 37258665 Free PMC article.
A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation.
Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, Chen J, Shmulevich I, Weissman JS, Curtis C, Califano A, Fu H, Crabtree GR, Kuo CJ. Lo YH, et al. Among authors: mah at. Cancer Discov. 2021 Jun;11(6):1562-1581. doi: 10.1158/2159-8290.CD-20-1109. Epub 2021 Jan 15. Cancer Discov. 2021. PMID: 33451982 Free PMC article.
The Intestinal Stem Cell Niche: Homeostasis and Adaptations.
Santos AJM, Lo YH, Mah AT, Kuo CJ. Santos AJM, et al. Among authors: mah at. Trends Cell Biol. 2018 Dec;28(12):1062-1078. doi: 10.1016/j.tcb.2018.08.001. Epub 2018 Sep 5. Trends Cell Biol. 2018. PMID: 30195922 Free PMC article. Review.
The LIN28B-IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine.
Chatterji P, Hamilton KE, Liang S, Andres SF, Wijeratne HRS, Mizuno R, Simon LA, Hicks PD, Foley SW, Pitarresi JR, Klein-Szanto AJ, Mah AT, Van Landeghem L, Gregory BD, Lengner CJ, Madison BB, Shah P, Rustgi AK. Chatterji P, et al. Among authors: mah at. Genes Dev. 2018 Aug 1;32(15-16):1020-1034. doi: 10.1101/gad.314369.118. Genes Dev. 2018. PMID: 30068703 Free PMC article.
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal.
Yan KS, Janda CY, Chang J, Zheng GXY, Larkin KA, Luca VC, Chia LA, Mah AT, Han A, Terry JM, Ootani A, Roelf K, Lee M, Yuan J, Li X, Bolen CR, Wilhelmy J, Davies PS, Ueno H, von Furstenberg RJ, Belgrader P, Ziraldo SB, Ordonez H, Henning SJ, Wong MH, Snyder MP, Weissman IL, Hsueh AJ, Mikkelsen TS, Garcia KC, Kuo CJ. Yan KS, et al. Among authors: mah at. Nature. 2017 May 11;545(7653):238-242. doi: 10.1038/nature22313. Epub 2017 May 3. Nature. 2017. PMID: 28467820 Free PMC article.
Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.
Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, Gholamin S, Reyes TF, Li R, Kuhnert F, Han X, Yuan J, Chiou SH, Brettman AD, Daly L, Corney DC, Cheshier SH, Shortliffe LD, Wu X, Snyder M, Chan P, Giffard RG, Chang HY, Andreasson K, Kuo CJ. Chang J, et al. Among authors: mah at. Nat Med. 2017 Apr;23(4):450-460. doi: 10.1038/nm.4309. Epub 2017 Mar 13. Nat Med. 2017. PMID: 28288111 Free PMC article.
20 results