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RNA base editing therapy cures hearing loss induced by OTOF gene mutation.
Xue Y, Tao Y, Wang X, Wang X, Shu Y, Liu Y, Kang W, Chen S, Cheng Z, Yan B, Xie Y, Bi L, Jia H, Li J, Xiao Q, Chen L, Yao X, Shi L, Yang H, Wu H. Xue Y, et al. Among authors: yao x. Mol Ther. 2023 Dec 6;31(12):3520-3530. doi: 10.1016/j.ymthe.2023.10.019. Epub 2023 Nov 2. Mol Ther. 2023. PMID: 37915172
Homology-mediated end joining-based targeted integration using CRISPR/Cas9.
Yao X, Wang X, Hu X, Liu Z, Liu J, Zhou H, Shen X, Wei Y, Huang Z, Ying W, Wang Y, Nie YH, Zhang CC, Li S, Cheng L, Wang Q, Wu Y, Huang P, Sun Q, Shi L, Yang H. Yao X, et al. Cell Res. 2017 Jun;27(6):801-814. doi: 10.1038/cr.2017.76. Epub 2017 May 19. Cell Res. 2017. PMID: 28524166 Free PMC article.
One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.
Zuo E, Cai YJ, Li K, Wei Y, Wang BA, Sun Y, Liu Z, Liu J, Hu X, Wei W, Huo X, Shi L, Tang C, Liang D, Wang Y, Nie YH, Zhang CC, Yao X, Wang X, Zhou C, Ying W, Wang Q, Chen RC, Shen Q, Xu GL, Li J, Sun Q, Xiong ZQ, Yang H. Zuo E, et al. Among authors: yao x. Cell Res. 2017 Jul;27(7):933-945. doi: 10.1038/cr.2017.81. Epub 2017 Jun 6. Cell Res. 2017. PMID: 28585534 Free PMC article.
CRISPR/Cas9-mediated targeted chromosome elimination.
Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J, Yang H. Zuo E, et al. Among authors: yao x. Genome Biol. 2017 Nov 24;18(1):224. doi: 10.1186/s13059-017-1354-4. Genome Biol. 2017. PMID: 29178945 Free PMC article.
Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing.
Yao X, Liu Z, Wang X, Wang Y, Nie YH, Lai L, Sun R, Shi L, Sun Q, Yang H. Yao X, et al. Cell Res. 2018 Mar;28(3):379-382. doi: 10.1038/cr.2018.9. Epub 2018 Jan 12. Cell Res. 2018. PMID: 29327726 Free PMC article. No abstract available.
11,200 results
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