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4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1H-pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells.
Masci D, Puxeddu M, Di Magno L, D'Ambrosio M, Parisi A, Nalli M, Bai R, Coluccia A, Sciò P, Orlando V, D'Angelo S, Biagioni S, Urbani A, Hamel E, Nocentini A, Filiberti S, Turati M, Ronca R, Kopecka J, Riganti C, Fionda C, Bordone R, Della Rocca G, Canettieri G, Supuran CT, Silvestri R, La Regina G. Masci D, et al. Among authors: ronca r. J Med Chem. 2023 Nov 9;66(21):14824-14842. doi: 10.1021/acs.jmedchem.3c01424. Epub 2023 Oct 30. J Med Chem. 2023. PMID: 37902628 Free PMC article.
TGF-β mediated drug resistance in solid cancer.
Turati M, Mousset A, Issa N, Turtoi A, Ronca R. Turati M, et al. Among authors: ronca r. Cytokine Growth Factor Rev. 2023 Jun-Aug;71-72:54-65. doi: 10.1016/j.cytogfr.2023.04.001. Epub 2023 Apr 11. Cytokine Growth Factor Rev. 2023. PMID: 37100675 Review.
Novel 2,4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors.
Kilbile JT, Sapkal SB, Renzi G, D'Agostino I, Cutarella L, Mori M, De Filippis B, Islam I, Massardi ML, Somenza E, Ronca R, Tamboli Y, Carta F, Supuran CT. Kilbile JT, et al. Among authors: ronca r. ACS Med Chem Lett. 2024 May 23;15(6):972-978. doi: 10.1021/acsmedchemlett.4c00206. eCollection 2024 Jun 13. ACS Med Chem Lett. 2024. PMID: 38894925
Benzoxaborinine, New Chemotype for Carbonic Anhydrase Inhibition: Ex Novo Synthesis, Crystallography, In Silico Studies, and Anti-Melanoma Cell Line Activity.
Giovannuzzi S, Nikitjuka A, Angeli A, Smietana M, Massardi ML, Turati M, Ronca R, Bonardi A, Nocentini A, Ferraroni M, Supuran CT, Winum JY. Giovannuzzi S, et al. Among authors: ronca r. J Med Chem. 2024 Oct 24;67(20):18221-18234. doi: 10.1021/acs.jmedchem.4c01516. Epub 2024 Oct 8. J Med Chem. 2024. PMID: 39378331
A recombinant fragment antigen-binding (Fab) of trastuzumab displays low cytotoxic profile in adult human cardiomyocytes: first evidence and the key implication of FcγRIIA receptor.
De Bartolo A, Romeo N, Marrone A, Rago V, Granieri MC, Vommaro ML, Cupelli A, Cerra MC, Indiveri C, Ronca R, Cantile M, Sanna R, Rocca C, Angelone T. De Bartolo A, et al. Among authors: ronca r. Acta Pharmacol Sin. 2024 Oct 16. doi: 10.1038/s41401-024-01397-3. Online ahead of print. Acta Pharmacol Sin. 2024. PMID: 39414958
140 results