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Page 1
New Flexible Analogues of 8-Aza-7-deazapurine Nucleosides as Potential Antibacterial Agents.
Khandazhinskaya A, Eletskaya B, Mironov A, Konstantinova I, Efremenkova O, Andreevskaya S, Smirnova T, Chernousova L, Kondrashova E, Chizhov A, Seley-Radtke K, Kochetkov S, Matyugina E. Khandazhinskaya A, et al. Among authors: konstantinova i. Int J Mol Sci. 2023 Oct 21;24(20):15421. doi: 10.3390/ijms242015421. Int J Mol Sci. 2023. PMID: 37895100 Free PMC article.
Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides.
Fateev IV, Kharitonova MI, Antonov KV, Konstantinova ID, Stepanenko VN, Esipov RS, Seela F, Temburnikar KW, Seley-Radtke KL, Stepchenko VA, Sokolov YA, Miroshnikov AI, Mikhailopulo IA. Fateev IV, et al. Among authors: konstantinova id. Chemistry. 2015 Sep 14;21(38):13401-19. doi: 10.1002/chem.201501334. Epub 2015 Jul 31. Chemistry. 2015. PMID: 26230190
Enzymatic synthesis of novel purine nucleosides bearing a chiral benzoxazine fragment.
Eletskaya BZ, Gruzdev DA, Krasnov VP, Levit GL, Kostromina MA, Paramonov AS, Kayushin AL, Muzyka IS, Muravyova TI, Esipov RS, Andronova VL, Galegov GA, Charushin VN, Miroshnikov AI, Konstantinova ID. Eletskaya BZ, et al. Among authors: konstantinova id. Chem Biol Drug Des. 2019 Apr;93(4):605-616. doi: 10.1111/cbdd.13458. Epub 2019 Jan 20. Chem Biol Drug Des. 2019. PMID: 30561886
Novel fleximer pyrazole-containing adenosine analogues: chemical, enzymatic and highly efficient biotechnological synthesis.
Khandazhinskaya A, Eletskaya B, Fateev I, Kharitonova M, Konstantinova I, Barai V, Azhayev A, Hyvonen MT, Keinanen TA, Kochetkov S, Seley-Radtke K, Khomutov A, Matyugina E. Khandazhinskaya A, et al. Among authors: konstantinova i. Org Biomol Chem. 2021 Sep 14;19(34):7379-7389. doi: 10.1039/d1ob01069g. Epub 2021 Jul 2. Org Biomol Chem. 2021. PMID: 34198312
Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A1 adenosine receptor agonists.
Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Paramonov AS, Kostromina MA, Zayats EA, Abramchik YA, Maltsev DV, Naumenko LV, Taran AS, Yakovlev DS, Spasov AA, Miroshnikov AI, Esipov RS, Konstantinova ID. Berzina MY, et al. Among authors: konstantinova id. Bioorg Chem. 2022 Sep;126:105878. doi: 10.1016/j.bioorg.2022.105878. Epub 2022 May 18. Bioorg Chem. 2022. PMID: 35660725
Rational Mutagenesis in the Lid Domain of Ribokinase from E. coli Results in an Order of Magnitude Increase in Activity towards D-arabinose.
Zayats EA, Fateev IV, Kostromina MA, Abramchik YA, Lykoshin DD, Yurovskaya DO, Timofeev VI, Berzina MY, Eletskaya BZ, Konstantinova ID, Esipov RS. Zayats EA, et al. Among authors: konstantinova id. Int J Mol Sci. 2022 Oct 19;23(20):12540. doi: 10.3390/ijms232012540. Int J Mol Sci. 2022. PMID: 36293391 Free PMC article.
Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro.
Eletskaya BZ, Berzina MY, Fateev IV, Kayushin AL, Dorofeeva EV, Lutonina OI, Zorina EA, Antonov KV, Paramonov AS, Muzyka IS, Zhukova OS, Kiselevskiy MV, Miroshnikov AI, Esipov RS, Konstantinova ID. Eletskaya BZ, et al. Among authors: konstantinova id. Int J Mol Sci. 2023 Mar 25;24(7):6223. doi: 10.3390/ijms24076223. Int J Mol Sci. 2023. PMID: 37047197 Free PMC article.
186 results