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Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance.
Sin JH, Sucharov J, Kashyap S, Wang Y, Proekt I, Liu X, Parent AV, Gupta A, Kastner P, Chan S, Gardner JM, Ntranos V, Miller CN, Anderson MS, Schjerven H, Waterfield MR. Sin JH, et al. Among authors: chan s. Sci Immunol. 2023 Oct 27;8(88):eabq3109. doi: 10.1126/sciimmunol.abq3109. Epub 2023 Oct 27. Sci Immunol. 2023. PMID: 37889983 Free PMC article.
Ikaros is critical for B cell differentiation and function.
Kirstetter P, Thomas M, Dierich A, Kastner P, Chan S. Kirstetter P, et al. Among authors: chan s. Eur J Immunol. 2002 Mar;32(3):720-30. doi: 10.1002/1521-4141(200203)32:3<720::AID-IMMU720>3.0.CO;2-P. Eur J Immunol. 2002. PMID: 11870616 Free article.
Ikaros regulates neutrophil differentiation.
Dumortier A, Kirstetter P, Kastner P, Chan S. Dumortier A, et al. Among authors: chan s. Blood. 2003 Mar 15;101(6):2219-26. doi: 10.1182/blood-2002-05-1336. Epub 2002 Oct 24. Blood. 2003. PMID: 12406904 Free article.
Visualizing PU.1 activity during hematopoiesis.
Back J, Allman D, Chan S, Kastner P. Back J, et al. Among authors: chan s. Exp Hematol. 2005 Apr;33(4):395-402. doi: 10.1016/j.exphem.2004.12.010. Exp Hematol. 2005. PMID: 15781329 Free article.
9,780 results